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Association between EGF +61 genetic polymorphisms and non-small cell lung cance...

Mello, Ramon Andrade de; Ferreira, Mónica; Costa, Sandra; Costa, Bruno Marques; Pires, Filipa Soares; Neves, Inês; Almeida, Maria Inês; Cunha, João

Epidermal growth factor (EGF) and its receptor play critical roles in non-small cell lung cancer (NSCLC) carcinogenesis. A functional polymorphism in the EGF gene has been linked to increased cancer susceptibility. This study aimed to evaluate the role of the EGF +61A/G polymorphism as risk factors in NSCLC patients. For the present case-control study, we analyzed 112 NSCLC and 126 cancer-free controls from Por...

Date: 2012   |   Origin: RepositóriUM - Universidade do Minho
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