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Clinical and Pathological Features of Double-Hit and Triple-Hit High-Grade B-Ce...
Almeida, Rui; Abrantes, Carlos; Gigliano, Davide; Oliveira, Rui Caetano; Teixeira, Paulo; Viegas, Marta; Rodrigues, Ângelo; Julião, Maria JoséBackground: High-grade B-cell lymphoma (HGBL) with rearrangements of MYC and BCL2 and/or BCL6, called double and triple-hit lymphomas (DTH-HGBL), are lymphoid malignancies with inferior outcomes when treated with standard chemotherapy. The identification of DTH-HGBL cases is challenging, considering their variable clinical, morphologic, and immunohistochemical features. Materials and Methods: Retrospective revi...
Data: 2022
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Origem: Estudo Geral - Universidade de Coimbra