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Surface modification of an intraocular lens material by plasma-assisted graftin...

Vieira, A. Paula; Pimenta, Andreia F. R.; Silva, Diana; Gil, M. Helena; Alves, Patrícia; Coimbra, Patrícia; Mata, José L. G. C.; Bozukova, Dimitriya

Endophthalmitis, an inflammation of the eye due to perioperative infection, may occur after cataract surgery. Intraocular lenses (IOLs) loaded with an antibiotic have been proposed as an alternative to the conventional postoperative endophthalmitis prophylaxis, since the antibiotic is delivered directly to the target site. In this work, an IOL-based antibiotic releasing system was prepared from a copolymer used...


Rheological Study of Genipin Cross-Linked Chitosan Hydrogels

Moura, M. José; Figueiredo, M. Margarida; Gil, M. Helena

This paper reports the rheological behavior of chitosan solutions that have been cross-linked with different amounts of genipin, at body temperature and physiological pH. The effect of the cross-linker loading on the rheological properties of hydrogels has been evaluated. The oscillatory time sweep method was used to monitor the dynamic viscoelastic parameters during in situ (i.e., in the rheometer) gelation ex...


Solution behaviour of lead(II) carboxylates in organic solvents

Burrows, Hugh D.; Miguel, Maria da Graça; Pereira, Rui P. C.; Proença, Nuno M. B.; Cardoso, Sónia M.C.; Geraldes, Carlos F. G. C.; Gil, M. Helena

The solution behaviour has been studied of a series of even chain length lead(II) carboxylates (octanoate to octadecanoate) and the odd chain length lead(II) heptadecanoate in a variety of non-complexing organic solvents and in alcohols. In agreement with previous studies, solubility increases dramatically above a certain temperature, which depends on solute concentration, chain length and solvent. This solutio...


Novel polymer-modified electrodes for batch injection sensors and application t...

Brett, Christopher M. A.; Fungaro, Denise A.; Morgado, José M.; Gil, M. Helena

Various polymer coatings have been investigated for the protection of mercury thin-film electrodes in the square wave anodic stripping voltammetry of environmental samples using batch injection analysis, with injection of untreated samples of volume 50 [mu]l directly over the sensing electrode. Polymer coatings studied include those with controlled porosity, and cation-exchange polymers based on sulphonated pol...


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