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Use of recombinant human deoxyribonuclease in pediatric intensive care unit – a...

Meireles,Daniel; Fernandes,Sofia Ribeiro; Sarmento,Alzira; Barbosa,Telma; Magalhães,Manuel Ferreira; Ramos,Ana; Fernandes,Paula Cristina

ABSTRACT Objective: Dornase alfa (rhDNase) reduces the viscosity of purulent sputum in the lungs. The use in patients with cystic fibrosis (CF) is proven. However, the evidence of its applicability to other conditions is limited. This study aims to present the authors’ experience with the use of rhDNase in non-CF patients admitted to the Pediatric Intensive Care Unit (PICU). At the study center, rhDNase was use...

Date: 2022   |   Origin: Oasisbr

Kawasaki disease in a five-month-old infant

Maciel,Juliana; Meireles,Daniel; Magalhães,Mariana; Gonçalves,Sara; Fernandes,Sofia Ribeiro; Fernandes,Paula Cristina

Abstract Introduction: Kawasaki disease, an acute self-limited vasculitis of small and medium arteries of unknown etiology, is the leading cause of heart disease in children in most developed countries. If untreated, it can lead to coronary artery dilatation and aneurysm, placing patients at risk for coronary thrombosis, myocardial infarction, or sudden death. Case Report: A previously healthy five-month-old bo...

Date: 2021   |   Origin: SciELO Portugal

Pediatric idiopathic midgut volvulus and shock in the infant

Maciel,Juliana; Santos,Ana Luísa; Marinho,Ana Sofia; Figueiredo,Susana; Araújo,Ana Rita; Morgado,Hélder; Leitão,Banquart; Sarmento,Alzira

Abstract Introduction: Intestinal volvulus is a surgical emergency in which a segment of the intestine twists over its mesenteric attachment, causing bowel obstruction. It usually presents with bilious vomiting and can progress to bowel necrosis and shock. Case Report: A 40-days-old male infant presented with acute onset irritability, bilious vomiting, abdominal distention, and hematochezia. He rapidly evolved ...

Date: 2020   |   Origin: SciELO Portugal

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