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Appraising animal models of prostate cancer for translational research: future ...

Nascimento-Gonçalves, E; Seixas, F; Gil da Costa, R; Pires, MJ; Neuparth, MJ; Moreira-Gonçalves, D; Fardilha, M; Faustino-Rocha, Ana I; Colaço, B

The growing incidence of prostate cancer has prompted a great investment in basic biology and translational studies to develop new therapies. Multiple animal models have been established to study etiological factors, cancer-preventive strategies and the molecular determinants of aggressiveness and metastases. The rat model of prostate cancer induced by chemical carcinogen N-methyl-N-nitrosourea (MNU) and testos...


Assessing the in vivo effects of Pteridium aquilinum extract in K14-HPV16 trans...

Medeiros-Fonseca, B; Faustino-Rocha, Ana I; Pires, MJ; Queiroga, F; Medeiros, R; Gil da Costa, R; Oliveira, PA

Pteridium aquilinum, commonly known as bracken fern, is a versatile plant species that thrive in diverse environmental conditions and has a global distribution. However, it possesses toxic properties that can lead to various diseases in animals. The consumption of bracken fern has been associated with the development of gastrointestinal and bladder tumours, thiamine deficiency, retinal degeneration, and haemorr...


Establishment of antibody panels and histochemical techniques in routine tumor ...

Pires, MA; Gama, A; Pires, I; Seixas, F; Prada, J; Pinto, ML; Branco, S; Vala, H; Delgado, L; Faísca, P; Carvalho, I; Lima, C; Ochoa, C; Orge, L

In Portugal, Veterinary Pathology is developing rapidly, and in recent years we assist to the emergence of private laboratories and the restructuring of universities,polytechnics and public laboratories.The Portuguese Society of Animal Pathology,through its actions and its associates has been keeping the discussion among its peers in order to standardizethe criteria of description,classification and evaluation ...


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