Background and Aim: Papillomaviruses (PVs) infections have been documented in numerous animal species across different regions worldwide. They often exert significant impacts on animal health and livestock production. Scientists have studied natural products for over half a century due to their diverse chemical composition, acknowledging their value in fighting cancer. Acorns (Quercus ilex) are believed to have...
This study explores a nanoemulsion formulated with açaí seed oil, known for its rich fatty acid composition and diverse biological activities. This study aimed to characterise a nanoemulsion formulated with açaí seed oil and explore its cytotoxic effects on HeLa and SiHa cervical cancer cell lines, alongside assessing its antioxidant and toxicity properties both in vitro and in vivo. Extracted from fruits sourc...
Background: Teratomas are rare types of germ cell neoplasms composed of various differentiated or undifferentiated tissues. Case Description: A 25-week-old female control FVB /n mouse in a 4-week toxicity study presented abdominal distension and poor body condition. It was euthanized, and the necropsy examination revealed a large mass connected to the tip of the right uterine horn, occupying the entire abdomina...
Papillomaviruses are small viruses able to cause disease not only in mammalians, but also in birds and reptiles. In recent years, a rising number of papillomaviruses have been identified in dogs and cats, totaling 24 canine papillomavirus (CPV) and six feline papillomavirus (FcaPV). The canine and feline papillomaviruses (CPVs and FcaPVs, respectively) are responsible for multiple lesions in these domestic spec...
nfections with certain types of papillomavirus, such as the human papillomavirus 16 (HPV16), are associated with the development of preneoplastic lesions and cancers of the anogenital, and head and neck regions. Cytinus hypocistis (L.) L. extracts are composed of substances presenting antiproliferative, antioxidant, anti-inflammatory and antibacterial properties, which might be promising as new therapeutic comp...
Pteridium aquilinum, commonly known as bracken fern, is a versatile plant species that thrive in diverse environmental conditions and has a global distribution. However, it possesses toxic properties that can lead to various diseases in animals. The consumption of bracken fern has been associated with the development of gastrointestinal and bladder tumours, thiamine deficiency, retinal degeneration, and haemorr...
Pteridium spp. (PTE) is a plant species that is very well adapted to environmental conditions. It is used as food by animals and various human populations. Its toxic chemical composition can induce various diseases upon acute or chronic consumption. Animals infected with papillomavirus that frequently feed on PTE tend to manifest a synergistic effect on lesions associated with this virus, since PTE has an immun...
Pteridium spp. (PTE) is a plant species that is very well adapted to environmental conditions. It is used as food by animals and various human populations. Its toxic chemical composition can induce various diseases upon acute or chronic consumption. Animals infected with papillomavirus that frequently feed on PTE tend to manifest a synergistic effect on lesions associated with this virus, since PTE has an immun...
Introduction Aloysia citrodora is used in folk medicine in the preparation of infusions due to its antispasmodic, digestive, sedative, and antipyretic properties. It also has antioxidant and antimicrobial properties.The present study evaluated the in vivo efficacy of aqueous extract (AE) of Aloysia citrodora in K14-HPV16 transgenic mice which HPV16 early genomic region and hence develop multiple-step epithelial...
Biochemical aspects of Pteridium spp. (bracken fern) toxicity in K14-HPV16 transgenic mice