52 documents found, page 1 of 6

Decoding the long-term safety of anti-CGRP (receptor) mAbs: a meta-analysis and...

Objective To evaluate the long-term safety (≥12months) of monoclonal antibodies (mAbs) targeting the calcitonin gene-related peptide (CGRP) or its receptor in migraine prevention by synthesising evidence from clinical trials and real-world studies. We focus on drug discontinuation due to adverse events and the type and frequency of adverse events. This is the first review to analyse the effects of the long-term...

WHO's global status report on neurology: mixed messages for people with headach...

International headache week 2026: march 15-21

Core Curriculum in Headaches for Neurologists: Proposal from the Portuguese Hea...

Continuous education in headaches is a priority for the Portuguese Headache Society. We present a proposal for a Core Curriculum in Headaches for Neurologists and Neurology-trainees, developed based on the ‘Headache Core Curriculum’ of the International Headache Society (IHS), revised in May 2020. This document is not merely a translation of the original but rather a structured adaptation to the national contex...

Gestão das cefaleias em Portugal: consenso das Sociedades Portuguesas de cefale...

As cefaleias são uma causa significativa de incapacidade a nível global, com a enxaqueca a ocupar o segundo lugar entre as doenças com mais anos vividos com incapacidade. A maioria dos doentes com cefaleias, incluindo enxaqueca, podem e devem ser diagnosticados, tratados e acompanhados eficazmente nos cuidados de saúde primários. Isso não só reduz a incapacidade associada a estas patologias, mas também previne ...

Hallmarks of primary headache: part 3 - cluster headache

Background: Cluster headache (CH) is a rare primary headache disorder characterized by recurrent episodes of strictly unilateral excruciating pain accompanied by trigemino-autonomic signs, which significantly impacts the quality of life, social interactions, and occupational functioning of those who are affected. To promote a better understanding of this disabling condition and to foster research on the topic, ...

The global campaign against headache, aged 21: a critical self-appraisal, and p...

Deciphering the mechanisms: pathophysiology of migraine-related cognitive dysfu...

Migraine is increasingly understood as a disorder of brain network dysfunction, where attack-related cognitive symptoms (attention deficits, slowed processing speed and executive dysfunction) can be as disabling as pain and may persist into the interictal period. Such symptoms are associated with functional and structural changes across the migraine cycle, involving the prefrontal cortex, thalamus, hypothalamus...

Longitudinal assessment of migraine burden in resistant and refractory migraine...

Background: Some individuals with migraine fail to respond adequately to preventive treatments, bearing most of migraine burden. The European Headache Federation (EHF) classifies these individuals into resistant migraine (ResM) or refractory migraine (RefM) according to treatment failures, debilitating headache days, and disease duration. We investigated the evolution of these categories over six months in pati...

Correction to: The role of community pharmacists in managing common headache di...

Correction: J Headache Pain 26, 100 (2025) In this article, the text “on behalf of the European Headache Federation, the Norwegian Centre for Headache Research (NorHead) and Lifting The Burden: the Global Campaign against Headache” has been removed from the author list because it erroneously duplicated text from the article title.