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The historical ecological background of West Nile virus in Portugal indicates O...

Geraldes, Martim; Cunha, Mónica; Godinho, Carlos; Lima, Ricardo; Giovanetti, Marta; Lourenço, José

West Nile (WNV) is a zoonotic arbovirus with an expanding geographical range and epidemic activity in Europe. Not having yet experienced a human-associated epidemic, Portugal remains an outlier in the Mediterranean basin. In this study, we apply ecological niche modelling informed by WNV historical evidence and a multitude of environmental variables from across Portugal. We identify that ecological backgrounds ...


The historical ecological background of West Nile virus in Portugal provides On...

Geraldes, Martim; Cunha, Mónica; Godinho, Carlos; Lima, Ricardo; Giovanetti, Marta; Lourenço, José

West Nile (WNV) is a zoonotic arbovirus with an expanding geographical range and epidemic activity in Europe. Not having yet experienced a human-associated epidemic, Portugal remains an outlier in the Mediterranean basin. In this study, we apply ecological niche modelling informed by WNV historical evidence (1969-2022) and a multitude of environmental variables from across Portugal. We identify that ecological ...


HIV-1 diversity and pre-treatment drug resistance in the era of integrase inhib...

Sebastião, Cruz S.; Abecasis, Ana B.; Jandondo, Domingos; Sebastião, Joana M.; Vigário, João; Comandante, Felícia; Pingarilho, Marta; Pocongo, Bárbara

The surveillance of drug resistance in the HIV-1 naïve population remains critical to optimizing the effectiveness of antiretroviral therapy (ART), mainly in the era of integrase strand transfer inhibitor (INSTI) regimens. Currently, there is no data regarding resistance to INSTI in Angola since Dolutegravir-DTG was included in the first-line ART regimen. Herein, we investigated the HIV-1 genetic diversity and ...


Exploring the urban arbovirus landscape in Rio de Janeiro, Brazil: transmission...

Schuab, Gabriel; Tosta, Stephane; Moreno, Keldenn; Fonseca, Vagner; Santos, Luciane Amorim; Slavov, Svetoslav Nanev; Kashima, Simone; Ciccozzi, Massimo

Background: This study focuses on urban arboviruses, specifically dengue (DENV), chikungunya (CHIKV), and Zika (ZIKV), which pose a significant public health challenge in Rio de Janeiro state, Southeast Brazil. In our research, we highlight critical findings on the transmission dynamics of these arboviruses in Rio de Janeiro, identifying distinct patterns of disease spread. Methods: By combining genomic data wi...


Population at risk of dengue virus transmission has increased due to coupled cl...

Nakase, Taishi; Giovanetti, Marta; Obolski, Uri; Lourenco, Jose

Dengue virus transmission has increased over the last four decades seemingly due to changes in climate, urbanization and population growth. Using estimates of dengue transmission suitability based on historical temperature and humidity data, we examined how shifts in these climatic variables and human population growth have contributed to the change in the geographical distribution and size of the global popula...


Insights into SARS-CoV-2 surveillance among prison populations in Mato Grosso d...

Silva, Liliane Ferreira da; Alcantara, Luiz Carlos Junior; Fonseca, Vagner; Frias, Diego; Zardin, Marina Castilhos Souza Umaki

This study examines the epidemiological and genomic characteristics, along with the transmission dynamics, of SARS-CoV-2 within prison units I and II in Campo Grande, Mato Grosso do Sul, Brazil. Conducted between May and October 2022, it reveals how the virus spreads in the confined settings of prisons, emphasizing the roles of overcrowded cells, frequent transfers, and limited healthcare access. The research i...


The historical ecological background of West Nile virus in Portugal indicates O...

Geraldes, Martim A.; Cunha, Mónica V.; Godinho, Carlos; Lima, Ricardo F. de; Giovanetti, Marta; Lourenço, José

West Nile (WNV) is a zoonotic arbovirus with an expanding geographical range and epidemic activity in Europe. Not having yet experienced a human-associated epidemic, Portugal remains an outlier in the Mediterranean basin. In this study, we apply ecological niche modelling informed by WNV historical evidence and a multitude of environmental variables from across Portugal. We identify that ecological backgrounds ...


Genomic and eco-epidemiological investigations in Uruguay reveal local Chikungu...

Burgueño, Analía; Giovanetti, Marta; Fonseca, Vagner; Morel, Noelia; Lima, Mauricio; Castro, Emerson; Guimarães, Natália R.; Iani, Felipe C. M.

Uruguay experienced its first Chikungunya virus outbreak in 2023, resulting in a significant burden to its healthcare system. We conducted analysis based on real-time genomic surveillance (30 novel whole genomes) to offer timely insights into recent local transmission dynamics and eco-epidemiological factors behind its emergence and spread in the country.


North–south pathways, emerging variants, and high climate suitability character...

Miguel, Isaac; Feliz, Edwin P.; Agramonte, Robinson; Martinez, Pedro V.; Vergara, Carlos; Imbert, Yvonne; Cruz, Lucia De la; Castro, Nurys de

Background: Dengue fever remains a significant public health challenge in tropical and subtropical regions, with its transmission dynamics being influenced by both environmental factors and human mobility. The Dominican Republic, a biodiversity hotspot in the Caribbean, has experienced recurrent dengue outbreaks, yet detailed understanding of the virus's transmission pathways and the impact of climatic factors ...


Dengue virus transmission in Italy: historical trends up to 2023 and a data rep...

Branda, Francesco; Nakase, Taishi; Maruotti, Antonello; Scarpa, Fabio; Ciccozzi, Alessandra; Romano, Chiara; Peletto, Simone

Dengue virus circulation is on the rise globally, with increased epidemic activity in previously unaffected countries, including within Europe. In 2023, global dengue activity peaked, and Italy reported the highest number of dengue cases and local chains of transmission to date. By curating several sources of information, we introduce a novel data repository focused on dengue reporting in Italy. We integrate da...


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