6 documents found, page 1 of 1
Position Statement of the Immunonephrology Working Group of the Portuguese Soci...
Nogueira, Estela; Oliveira, Nuno; Godinho, Iolanda; Lança, Alice; Inácio, António; Santos, Clara; Pinto, Helena; Laranjinha, Ivo; Vaz, RaquelSystemic lupus erythematosus (SLE) is a challenging immune ‑mediated disease that frequently involves the kidney as lupus nephritis (LN), an immune complex glomerulonephritis. Its occurrence is associated with increased morbidity and mortality and current treatment still fails to preserve renal function in the long term. As such, more efficacious and less toxic treatments are needed to treat LN, aiming to reduc...
Real-World Experience with Avacopan in ANCA-Associated Vasculitis in Portugal
Oliveira Correia, Sofia; Laranjinha, Ivo; Nogueira, Estela; Cunha, Anita; Tenazinha, Catarina; Pinto, Helena; Ferreira, Inês; Fernandes Serodio, JoãoIntroduction: Avacopan, a selective C5a receptor inhibitor, has emerged as a potential corticosteroid-sparing treatment in ANCA-associated vasculitis (AAV). This study aims to evaluate its real-world efficacy and safety in Portuguese patients with active AAV. Methods: We conducted a multicenter retrospective analysis of 15 adult patients with newly diagnosed or relapsing AAV treated with avacopan across nine ac...
The Critical Role of Multidisciplinary Teams inthe Management of Rare Systemic ...
Ferreira, Inês; Nogueira, Estela; Laranjinha, Ivo; Moura Jerónimo, Teresa; Godinho, Iolanda; Inácio, António; Oliveira Correia, Sofia; Lança, AliceRare systemic rheumatic diseases (RISD) with renal involvement, such as anti‑neutrophil cytoplasmic antibody (ANCA)‑associated vasculitis and systemic lupus erythematosus, require complex, coordinated care. These conditions often involve renal complications requiring specialized and timely intervention. Traditional care models, typically fragmented across specialties, are insufficient to meet the nuanced needs ...
Nephrotic syndrome in pregnant diabetic women: maternal and perinatal outcomes ...
Nogueira, Estela; Afonso, Rita; Godinho, Iolanda; Centeno, Mónica; Pinto, Luísa; Lopes, José AntónioManagement of pregnant women with diabetic kidney disease and nephrotic range proteinuria or nephrotic syndrome constitute a challenge to clinicians. Maternal and perinatal outcomes, especially in patients with chronic kidney disease, remain poor. The authors describe the multidisciplinary approach and the outcomes of diabetic pregnant patients with nephrotic range proteinuria.
Obesity, acute kidney injury and mortality in patients with sepsis: a cohort an...
Gameiro, Joana; Gonçalves, Miguel; Pereira, Marta; Rodrigues, Natacha; Godinho, Iolanda; Neves, Marta; Gouveia, João; Silva, Zélia Costa e; Jorge, SofiaAlthough the prognostic effect of obesity has been studied in critically ill patients its impact on outcomes of septic patients and its role as a risk factor for acute kidney injury (AKI) is not consensual. We aimed to analyze the impact of obesity on the occurrence of AKI and on in-hospital mortality in a cohort of critically ill septic patients. This study is retrospective including 456 adult patients with se...
Letter to the Editor. Use of Vitamin K Antagonists in Patients on Hemodialysis:...
Godinho, Iolanda; Weigert, André- / -; - / -