45 documents found, page 1 of 5

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Assessing the Genotoxicity of Cellulose Nanomaterials in a Co-Culture of Human ...

Ventura, Célia; Pinto, Fátima V.; Lourenço, Ana Filipa; Pedrosa, Jorge F. S.; Fernandes, Susete N.; da Rosa, Rafaela R.; Godinho, Maria Helena

Cellulose micro/nanomaterials (CMNMs) are innovative materials with a wide spectrum of industrial and biomedical applications. Although cellulose has been recognized as a safe material, the unique properties of its nanosized forms have raised concerns about their safety for human health. Genotoxicity is an endpoint that must be assessed to ensure that no carcinogenic risks are associated with exposure to nanoma...


Assessing the Genotoxicity of Cellulose Nanomaterials in a Co-Culture of Human ...

Ventura, Célia; Pinto, Fátima; Lourenço, Ana Filipa; Pedrosa, Jorge F. S.; Fernandes, Susete N.; da Rosa, Rafaela R.; Godinho, Maria Helena

Cellulose micro/nanomaterials (CMNMs) are innovative materials with a wide spectrum of industrial and biomedical applications. Although cellulose has been recognized as a safe material, the unique properties of its nanosized forms have raised concerns about their safety for human health. Genotoxicity is an endpoint that must be assessed to ensure that no carcinogenic risks are associated with exposure to nanoma...


Genotoxicity of Three Micro/Nanocelluloses with Different Physicochemical Chara...

Ventura, Célia; Marques, Catarina; Cadete, João; Vilar, Madalena; Pedrosa, Jorge F. S.; Pinto, Fátima; Fernandes, Susete Nogueira

Background: Nanocellulose is an innovative engineered nanomaterial with an enormous potential for use in a wide array of industrial and biomedical applications and with fast growing economic value. The expanding production of nanocellulose is leading to an increased human exposure, raising concerns about their potential health effects. This study was aimed at assessing the potential toxic and genotoxic effects ...


Analysis of the In Vitro Toxicity of Nanocelluloses in Human Lung Cells as Comp...

Pinto, Fátima V.; Lourenço, Ana Filipa; Pedrosa, Jorge F. S.; Gonçalves, Lídia; Ventura, Célia; Vital, Nádia; Bettencourt, Ana; Fernandes, Susete N.

Cellulose micro/nanomaterials (CMNM), comprising cellulose microfibrils (CMF), nanofibrils (CNF), and nanocrystals (CNC), are being recognized as promising bio-nanomaterials due to their natural and renewable source, attractive properties, and potential for applications with industrial and economical value. Thus, it is crucial to investigate their potential toxicity before starting their production at a larger ...


Genotoxicity of Three Micro/Nanocelluloses with Different Physicochemical Chara...

Ventura, Célia; Marques, Catarina; Cadete, João; Vilar, Madalena; Pedrosa, Jorge F.S.; Pinto, Fátima; Fernandes, Susete Nogueira; da Rosa, Rafaela Raupp

Background: Nanocellulose is an innovative engineered nanomaterial with an enormous potential for use in a wide array of industrial and biomedical applications and with fast growing economic value. The expanding production of nanocellulose is leading to an increased human exposure, raising concerns about their potential health effects. This study was aimed at assessing the potential toxic and genotoxic effects ...


Analysis of the In Vitro Toxicity of Nanocelluloses in Human Lung Cells as Comp...

Pinto, Fátima; Lourenço, Ana Filipa; Pedrosa, Jorge F.S.; Gonçalves, Lídia; Ventura, Célia; Vital, Nádia; Bettencourt, Ana; Fernandes, Susete N.

Cellulose micro/nanomaterials (CMNM), comprising cellulose microfibrils (CMF), nanofibrils (CNF), and nanocrystals (CNC), are being recognized as promising bio-nanomaterials due to their natural and renewable source, attractive properties, and potential for applications with industrial and economical value. Thus, it is crucial to investigate their potential toxicity before starting their production at a larger ...


Investigation of potential respiratory adverse effects of micro/nanofibrillated...

Pinto, Fátima; Ventura, Célia; Cadete, João; Lourenço, Ana Filipa; Pedrosa, Jorge F.S.; Vital, Nádia; Pereira, Joana F.S.; Matos, Paulo

Micro/nanofibrillated (CMF/CNF) and nanocrystalline (CNC) celluloses are innovative materials with enormous potential for industrial and biomedical applications. Their expanding production/application urges the investigation of their safety for human health. This study aimed at investigating the potential respiratory outcomes of two CMF/CNF and one CNC produced from bleached Eucalyptus globulus kraft pulp using...


Toxicidade da nanocelulose em modelos in vitro: um contributo para a avaliação ...

Ventura, Célia; Pinto, Fátima; Marques, Catarina; Cadete, João; Vilar, Madalena; Lourenço, Ana Filipa; Pedrosa, Jorge F. S.; Fernandes, Susete N.

As nanoceluloses são nanomateriais inovadores com potencial para uma vasta gama de aplicações industriais e biomédicas. No entanto, a expansão da sua produção tem vindo a suscitar preocupações quanto aos possíveis efeitos, a longo prazo, na saúde humana. Este estudo teve como objetivo avaliar a segurança de algumas nanoceluloses produzidas a partir de matéria-prima nacional, através da caracterização da sua pot...


Analysis of the In Vitro Toxicity of Nanocelluloses in Human Lung Cells as Comp...

Pinto, Fátima; Lourenço, Ana Filipa; Pedrosa, Jorge; Gonçalves, Lídia; Ventura, Célia; Vital, Nádia; Bettencourt, Ana; Fernandes, Susete N.

Cellulose micro/nanomaterials (CMNM), comprising cellulose microfibrils (CMF), nanofibrils (CNF), and nanocrystals (CNC), are being recognized as promising bio-nanomaterials due to their natural and renewable source, attractive properties, and potential for applications with industrial and economical value. Thus, it is crucial to investigate their potential toxicity before starting their production at a larger ...


On the influence of imidazolium ionic liquids on cellulose derived polymers

Paiva, Tiago; Echeverria Zabala, Coro; Godinho, Maria Helena; Almeida, Pedro L.; Corvo, Marta C.

The demand for better cellulose solvents has driven the search for new and improved materials to enable the processing of this polysaccharide. Ionic liquids have been debated for a long time as interesting alternatives, but the molecular details on the solubilization mechanism have been a matter of controversy. Herein, for the first time, the structure and dynamics of hydroxypropylcellulose (HPC) liquid crystal...


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