6 documents found, page 1 of 1
SGLT-2 Inhibitors and Renal Outcomes in Non-Diabetic Patients: A Systematic Review
Sousa,Mariana Silva de; Almeida,Cristiana Maia de; Marchão,Natália; Godinho,Iolanda; Lopes,José António; Gameiro,JoanaABSTRACT Introduction: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have shown positive renal outcomes in diabetic patients. There is also emerging evidence in non-diabetic patients. This review was conducted to analyse the renal outcomes of SGLT2i in patients without diabetes mellitus (DM). Methods: A systematic review was performed in a Preferred Reporting Items for Systematic Reviews and Meta-Analyses ...
Rituximab in glomerular diseases: a case series and narrative review
Duarte,Inês; Oliveira,João; Outerelo,Cristina; Godinho,Iolanda; Pereira,Marta; Fernandes,Paulo; Jorge,Sofia; Gameiro,JoanaAbstract Introduction: The use of Rituximab (RTX) in glomerular diseases (GD) has increased in the past years, although it is still only used in a small fraction of patients. Methods: A single center retrospective study of adult patients with membranous nephropathy (MN), focal segmental glomerulosclerosis (FSGS), lupus nephritis (LN), and vasculitis treated with RTX as first or second-line therapy was conducted...
In utero diagnosis of Autosomal Dominant Polycystic Kidney Disease
Cal,Margarida; Godinho,Iolanda; Sá,Mariana Soeiro e; Cunha,Margarida; Carvalho,Rui Marques deAutosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common inherited renal disease; its diagnosis, which used to be made during adulthood, has shifted towards earlier ages due to the development and widespread use of ultrasonography. Very-early onset (VEO) cases represent a high-risk group of patients. We describe a case of prenatal diagnosis in a pregnant woman with ADPKD. This case shows how diag...
Life-saving vascular access in vascular capital exhaustion: single center exper...
Pereira,Marta; Lopez,Noélia; Godinho,Iolanda; Jorge,Sofia; Nogueira,Estela; Neves,Fernando; Fortes,Alice; Costa,António G.Abstract Introduction: Intra-atrial catheter (IAC) placement through an open surgical approach has emerged as a life-saving technique in hemodialysis (HD) patients with vascular access exhaustion. Objective: To assess the complications of IAC placement, as well as patient and vascular access survival after this procedure. Methods: The authors retrospectively analyzed all seven patients with vascular capital exh...
Hyperinfection syndrome with hypereosinophilia and chronic kidney disease: case...
Lopez,Noélia; Fortes,Alice; Nogueira,Estela; Godinho,Iolanda; Jorge,Sofia; Marques,Tiago; Fernandes,Paulo; Costa,António GChronic kidney disease (CKD) is associated to significant infection incidence and severity, the cause of death of, approximately, 20% of end-stage renal disease patients. Close to 80% of all infections in these patients can be related to organ or tissue other than vascular access, reflecting immune system dysfunction related to several mechanisms. Strongyloides stercoralis is an endemic nematode found especiall...
Onset of psychosis at age 81? With regard to frontal lobe syndromes
Pedro,Patrícia; Telles-Correia,Diogo; Godinho,Iolanda; Chagas,CarlosWhen the frontal lobe of the brain is affected important behavioral changes may occur mainly at the level of executive functioning, i.e., planning, decision-making, judgment and self-perception. However, the behavioral changes may be of different nature with marked indifference and apathy. We report a clinical case of an 81-year-old patient with sudden onset of behavioral changes that were initially interpreted...