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Burden of disease associated with dietary exposure to carcinogenic aflatoxins i...

Martins, Carla; Vidal, Arnau; De Boevre, M.; De Saeger, Sarah; Nunes, Carla; Torres, Duarte; Goios, A.; Lopes, Carla; Alvito, Paula; Assunção, Ricardo

Human biomonitoring is an important tool to assess human exposure to chemicals, contributing to describe trends of exposure over time and to identify population groups that could be under risk. Aflatoxins are genotoxic and carcinogenic food contaminants causing hepatocellular carcinoma, the third leading cause of cancer deaths worldwide. In Portugal, scarce data are available regarding exposure to aflatoxins an...


Food Consumption Data as a Tool to Estimate Exposure to Mycoestrogens

Martins, C; Torres, Duarte; Lopes, C; Correia, D; Goios, A.; Assuncao, R; Alvito, P; Vidal, A; De Boevre, M; De Saeger, S; Nunes, C

Zearalenone and alternariol are mycotoxins produced by Fusarium and Alternaria species, respectively, that present estrogenic activity and consequently are classified as endocrine disruptors. To estimate the exposure of the Portuguese population to these two mycotoxins at a national level, a modelling approach, based on data from 94 Portuguese volunteers, was developed considering as inputs: i) the food consump...


Exposure assessment of Portuguese population to multiple mycotoxins: the human ...

Martins, Carla; Vidal, A.; De Boevre, M.; De Saeger, S.; Nunes, C.; Torres, D.; Goios, A.; Lopes, C.; Assunção, R; Alvito, P.

Mycotoxins constitute a relevant group of food contaminants with several associated health outcomes such as estrogenic, immunotoxic, nephrotoxic and teratogenic effects. Although scarce data are available in Portugal, human biomonitoring studies have been globally developed to assess the exposure to mycotoxins at individual level. In order to overcome this lack of data, the present study concerned the analysis ...


Human biomonitoring of multiple mycotoxins in the Portuguese population: streng...

Martins, Carla; De Boevre, Marthe; De Saeger, Sarah; Nunes, Carla; Torres, Duarte; Goios, A.; Lopes, Carla; Assunção, Ricardo; Alvito, Paula; Vidal, A.

Mycotoxins constitute a relevant group of food contaminants with associated health outcomes such as estrogenic, immunotoxic, nephrotoxic and teratogenic effects. Although scarce data are available in Portugal, human biomonitoring (HBM) studies have been globally developed to assess the exposure to mycotoxins at individual level. This study aimed to present data for mycotoxins’ urinary biomarkers within a human ...


Mycotoxins in adult population from Portugal: Overall results and determinants ...

Vidal, Arnau; De Saeger, Sarah; Sarah, De Saeger; Nunes, Carla; Torres, D.; Goios, A.; Lopes, Carla; Assunção, Ricardo; Alvito, Paula; De Boevre, Marthe

Human biomonitoring (HBM) is recognized as an important tool to assess the Human exposure to chemicals, contributing to describe trends and patterns of exposure over time and to identify population groups that could be under risk. Mycotoxins, fungi secondary metabolites that produce toxic effects in humans, are important compounds found in foods usually consumed worldwide in a daily basis. In Portugal, scarce d...


Exposure of Portuguese population to mycoestrogens: a public health concern?

Martins, Carla; Vidal, Arnau; De Saeger, Sarah; Nunes, Carla; Torres, D.; Goios, A.; Lopes, C.; Assunção, Ricardo; Alvito, Paula; De Boevre, M.

Alternariol (AOH) and zearalenone (ZEN) are mycotoxins that occur widely in food commodities, with particular incidence in cereals [1,2]. Both mycotoxins present estrogenic effects, therefore, it is crucial to assess the human exposure and the associated risk [2,3]. To date, there is a lack of human studies to assess exposure to ZEN and AOH through biomarkers analysis in Portugal. In the scope of the National F...


Exposure of Portuguese population to aflatoxins: the contribution of human biom...

Martins, Carla; Vidal, Arnau; De Boevre, M.; De Saeger, S.; Nunes, Carla; Torres, D.; Goios, A.; Lopes, C.; Alvito, Paula; Assunção, Ricardo

Human biomonitoring (HBM) is recognized as an important tool to assess the Human exposure to chemicals, contributing to describe trends and patterns of exposure over time and to identify population groups that could be under risk. Natural chemicals as mycotoxins, fungi metabolites that produce toxic effects in humans, are important compounds that could be found in foods usually consumed worldwide in a daily bas...


Burden of disease attributable to exposure to aflatoxins in Portugal

Martins, Carla; Vidal, Arnau; De Boevre, M.; De Saeger, Sarah; Nunes, Carla; Torres, D.; Goios, A.; Lopes, Carla; Alvito, Paula; Assunção, Ricardo

Human biomonitoring (HBM) is recognized as an important tool to assess the Human exposure to chemicals, contributing to describe trends and patterns of exposure over time and to identify population groups that could be under risk. Natural chemicals as mycotoxins, fungi metabolites that produce toxic effects in humans, are important compounds that could be found in foods usually consumed worldwide in a daily bas...


Exposure to mycoestrogens a public health concern in Portugal

Martins, Carla; Vida, Arnau; De Saeger, Sarah; Nunes, Carla; Torres, D.; Goios, A.; Lopes, Carla; Assunção, Ricardo; Alvito, Paula; De Boevre, M.

Alternariol (AOH) and zearalenone (ZEN) are mycotoxins that occur widely in food commodities, with particular incidence in cereals [1,2]. Both mycotoxins present estrogenic effects, therefore, it is crucial to assess the human exposure and the associated risk [2,3]. To date, there is a lack of human studies to assess exposure to ZEN and AOH through biomarkers analysis in Portugal. In the scope of the National F...


Risk assessment of Portuguese population to multiple mycotoxins: the human biom...

Martins, Carla; Vidal, Arnau; De Boevre, Marthe; De Saeger, Sarah; Nunes, Carla; Torres, D.; Goios, A.; Lopes, Carla; Alvito, Paula; Assunção, Ricardo

Mycotoxins constitute a relevant group of food contaminants with several associated health outcomes such as estrogenic, immunotoxic, nephrotoxic and teratogenic effects. Although scarce data are available in Portugal, human biomonitoring studies have been globally developed to assess the exposure to mycotoxins at individual level. The present study concerned the analysis of mycotoxins in 24h urine and first-mor...


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