49 documents found, page 1 of 5
Functional properties of transparent ZnO thin films synthetized by using spray ...
Cuadra, J. G.; Estrada, Ana C.; Oliveira, C.; Abderrahim, L. A.; Porcar, S.; Fraga, D.; Trindade, T.; Seabra, M. P.; Labrincha, J.; Carda, J. B.Spray pyrolysis is a promising method for producing thin, transparent films on glass substrates. ZnO thin films synthesized by this method exhibit high crystallinity, adhesion and chemical resistance. They also possess the ability to degrade water pollutants and exhibit antibacterial properties under UV light. The crystalline structure of these films has been studied using grazing X-ray diffraction (GIXRD), ato...
Multifunctional silver-coated transparent TiO2 thin films for photocatalytic an...
Cuadra, J. G.; Molina-Prados, S.; Mínguez-Vega, Gladys; Estrada, Ana.C.; Trindade, T.; Oliveira, C.; Seabra, M. P.; Labrincha, J.; Porcar, S.Transparent TiO2 thin films coated with Ag NPs were synthesized using two industrially applicable techniques,pulsed laser ablation (PLAL) and spray pyrolysis without using high vacuum. These transparent thin films were deposited on glass in order to generate glass materials with photocatalytic and antimicrobial properties and a minimum loss of transparency. The structural, morphological and optical properties o...
Biological effects and bioaccumulation of gold in gilthead seabream (Sparus aur...
Barreto, A.; Dias, A. A.; Duarte, B.; Pinto, Edgar; Almeida, A.; Trindade, T.; Soares, A. M. V. M.; Hylland, K.; Loureiro, S.; Oliveira, M.The question of whether gold (Au) is more toxic as nanoparticles or in its ionic form remains unclear and controversial. The present work aimed to clarify the effects of 96 h exposure to 4, 80 and 1600 μg·L−1 of 7 nm gold nanoparticles (AuNPs) – (citrate coated (cAuNPs) or polyvinylpyrrolidone coated (PVP-AuNPs)) – and ionic Au (iAu) on gilthead seabream (Sparus aurata). Effects at different levels of biologica...
Effects of gold nanoparticles in gilthead seabream—A proteomic approach
Barreto, A.; Carvalho, A.; Campos, A.; Osório, H.; Pinto, Edgar; Almeida, A.; Trindade, T.; Soares, A. M. V. M.; Hylland, H.; Loureiro, S.; Oliveira, M.Despite the widespread use of nanoparticles (NPs), there are still major gaps of knowledge regarding the impact of nanomaterials in the environment and aquatic animals. The present work aimed to study the effects of 7 and 40 nm gold nanoparticles (AuNPs) – citrate and polyvinylpyrrolidone (PVP) coated – on the liver proteome of the estuarine/marine fish gilthead seabream (Sparus aurata). After 96 h, exposure to...
Effects of single and combined exposures of gold (nano versus ionic form) and g...
Barreto, A.; Carvalho, A.; Silva, D.; Pinto, E.; Almeida, A.; Paíga, P.; Correia-Sá, L.; Delerue-Matos, C.; Trindade, T.; Soares, A.M.V.M.; Hylland, K.In vitro methods have gained rising importance in ecotoxicology due to ethical concerns. The aim of this study was to assess the single and combined in vitro effects of gold, as nanoparticle (AuNPs) and ionic (Au+) form, and the pharmaceutical gemfibrozil (GEM). Sparus aurata liver organ culture was exposed to gold (4 to 7200 μg·L−1), GEM (1.5 to 15,000 μg·L−1) and combination 80 μg·L−1 gold +150 μg·L−1 GEM for...
Biological effects and bioaccumulation of gold in gilthead seabream (sparus aur...
Barreto, A; Dias, A.; Duarte, B.; Pinto, E.; Almeida, A.; Trindade, T.; Soares, A. M. V. M.; Hylland, K.; Loureiro, S.; Oliveira, M.The question of whether gold (Au) is more toxic as nanoparticles or in its ionic form remains unclear and controversial. The present work aimed to clarify the effects of 96 h exposure to 4, 80 and 1600 μg·L-1 of 7 nm gold nanoparticles (AuNPs) - (citrate coated (cAuNPs) or polyvinylpyrrolidone coated (PVP-AuNPs)) - and ionic Au (iAu) on gilthead seabream (Sparus aurata). Effects at different levels of biologica...
Genotoxicity of gold nanoparticles in the gilthead seabream (Sparus aurata) aft...
Barreto, A.; Luis, L.G.; Pinto, E.; Almeida, A.; Paíga, Paula; H.M.L.M. Santos, Lúcia; Delerue-Matos, Cristina; Trindade, T.; Soares, A.M.V.M.Due to their diverse applications, gold nanoparticles (AuNPs) are expected to increase of in the environment, although few studies are available on their mode of action in aquatic organisms. The genotoxicity of AuNPs, alone or combined with the human pharmaceutical gemfibrozil (GEM), an environmental contaminant frequently detected in aquatic systems, including in marine ecosystems, was examined using gilthead ...
Effects and bioaccumulation of gold nanoparticles in the gilthead seabream (Spa...
Barreto, A.; Luis, L.G.; Pinto, E.; Almeida, A.; Paíga, Paula; Santos, Lúcia H.M.L.M.; Delerue-Matos, Cristina; Trindade, T.; Soares, A.M.V.M.Gold nanoparticles (AuNPs) are found in a wide range of applications and therefore expected to present increasing levels in the environment. There is however limited knowledge concerning the potential toxicity of AuNPs as well as their combined effects with other pollutants. Hence, the present study aimed to investigate the effects of AuNPs alone and combined with the pharmaceutical gemfibrozil (GEM) on differe...
Recovery and Purification of (Bio)Pharmaceuticals Using (Nano)Materials
Tavares, A. P. M.; Neves, M. C.; Trindade, T.; Freire, M. G.Biopharmaceuticals main classes comprise recombinant proteins, antibodies, and nucleic-acid-derived products, while synthetic pharmaceuticals include a wide variety of organic compounds. The purification of (bio)pharmaceuticals, as part of downstream processing, is mainly carried out by chromatographic processes, which are responsible for the therapeutics high cost. Therefore, there is a crucial need on the dev...
Supported ionic liquids for the removal of cyclophosphamide from aqueous solutions
Rocha, B.; Neves, M. C.; Sousa, A. C.; Trindade, T.; Freire, M. G.The incidence of cancer is increasing and with it also the consumption of anti-cancer drugs. As with other drugs, these compounds are not completely metabolized and are excreted through the urine, ultimately reaching waste water treatment plants (WWTPs). Anti-cancer drugs are emerging pollutants, reinforcing the need for developing effective treatment or removal strategies. This work aims to contribute to the d...