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Unveiling potential functional applications of grape pomace extracts based on t...

<jats:title>Abstract</jats:title> <jats:p>Grape pomace (GP), a by-residue from the wine industry, contains bioactive molecules such as phenolic compounds, and anthocyanins, among others, with potential health benefits. In the current study, these bioactive molecules were extracted from GP of different <jats:italic>Vitis vinifera L.</jats:italic> varieties (Tinta Negra, Complexa, Malvasia Roxa, Malvasia, Sercial...

Unlocking the fatty acid and antioxidant profile of grape pomace: a systematic ...

<jats:p>Grape pomace (GP), the main by-product of the wine industry, represents a valuable source of bioactive metabolites with significant potential for valorization in the context of sustainable bioresource management. This study systematically characterizes the fatty acid methyl ester (FAME) profile, total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activities (DPPH, ABTS, ORAC) of...

Grape pomace as a renewable natural biosource of value-added compounds with pot...

<jats:p>Growing consumer demand for environmentally conscious, sustainable, and helpful products has prompted scientists and industry experts worldwide to look for inventive approaches to mitigate the environmental impact, particularly concerning agricultural and industrial waste. Among the by-products of winemaking, grape pomace (skins, seeds, stems) has the potential to be economically valuable as it is rich ...

Tracing the volatilomic fingerprint of grape pomace as a powerful approach for ...

The huge amount of grape pomace (GP) generated every year worldwide, particularly in Europe, creates negative impacts at the economic and environmental levels. As far as we know, scarce research has been done on the volatilomic fingerprint of GP. To meet consumer demand for healthy foods, there is a growing interest in the characterization of particular volatile organic metabolites (VOMS) in GP that can be used...

The fingerprint of fortified wines—From the sui generis production processes to...

<jats:p>The fortified wines that originated in Mediterranean countries have, in common, a high alcohol content to increase their shelf-life during long journeys to northern Europe and the American continent. Nowadays, the world’s better-known wines, including Marsala, Madeira, Port, and Sherry, due to their high alcoholic content, sweet taste, and intense aromatic profile, are designated as dessert wines and so...

GMP-grade nanoparticle targeted to nucleolin downregulates tumor molecular sign...

Patients with breast or ovarian cancer have not benefited from improved efficacy with pegylated liposomal doxorubicin relative to free drug, likely due to the limited extent of the enhanced permeability and retention (EPR) effect, further compromising drug bioavailability in the tumor. Herein it is hypothesized that targeting nucleolin overexpressed in tumor endothelial cells (readily accessible from the vascul...

The flavor chemistry of fortified wines: a comprehensive approach

For centuries, wine has had a fundamental role in the culture and habits of different civilizations. Amongst numerous wine types that involve specific winemaking processes, fortified wines possess an added value and are greatly honored worldwide. This review comprises the description of the most important characteristics of the main worldwide fortified wines—Madeira, Port, Sherry, Muscat, and Vermouth—structure...

Computing risks. Physicians do it better?

Michael Jackson: O artista perfeito

No decorrer desta tese, abordam-se conhecimentos psicanalíticos aplicados à arte e aos artistas, mais especialmente em relação à área da música, mas que obviamente poderão ser estendidos a outras áreas artísticas. São expostas várias teorias psicanalíticas, oriundas de vários autores de renome e que nos ajudarão a compreender qual a função da arte e quais as qualidades ou características intrínsecas a um artist...