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Characterization of NS5A and NS5B Resistance-Associated Substitutions from Geno...

Ruben, Brandão,; Rute, Marcelino,; Goncalves, Maria de Fátima; Diogo, Isabel; Carvalho, A P; Cabanas, Joaquim; Costa, Inês; Brogueira, Pedro; Ventura, F

This study is focused on the prevalent NS5 coding region resistance-associated substitutions (RASs) in DAA-naive genotype (GT)1 HCV-infected patients and their potential impact on success rates. Plasma RNA from 81 GT1 HCV-infected patients was extracted prior to an in-house nested RT-PCR of the NS5 coding region, which is followed by Sanger population sequencing. NS5A RASs were present in 28.4% (23/81) of all G...

Date: 2018   |   Origin: Repositório Institucional da UNL
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A21 HIV-1 sub-subtype F1 outbreak among MSM in Belgium

Vinken, L; Fransen, K; Pineda-Peña, A C; Alexiev, I; Balotta, C; Debaisieux, L; Devaux, C; García Ribas, S; Gomes, P; Incardona, F; Kaiser, R; Ruelle, J

Date: 2017   |   Origin: Repositório Institucional da UNL
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