6 documents found, page 1 of 1
Exploring Demand: Challenges and Opportunities for Free-From and Organic Foods ...
Lemos, T; Vasconcelos, M; Sousa, S; Pinho, S; Gomes, AM; Pinto, EThe rising prevalence of food intolerances and increased health and environmental consciousness has driven the demand for free-from (FF) and organic products. This study aims to analyze consumer needs, motivations, and challenges related to these products in Portugal through an online survey with 2268 eligible responses, with a median age of the participants of 41 years. The sample was predominantly female (76....
An anaphase surveillance mechanism prevents micronuclei formation from frequent...
Orr, B; Sousa, F; Gomes, AM; Afonso, O; Ferreira, LT; Figueiredo, AC; Maiato, HMicronuclei are a hallmark of cancer and several other human disorders. Recently, micronuclei were implicated in chromothripsis, a series of massive genomic rearrangements that may drive tumor evolution and progression. Here, we show that Aurora B kinase mediates a surveillance mechanism that integrates error correction during anaphase with spatial control of nuclear envelope reassembly to prevent micronuclei f...
A culture-sensitive semi-quantitative FFQ for use among the adult population in...
Vila-Real, C; Pimenta-Martins, A; Magu, JS; Kunyanga, C; Mbugua, S; Katina, K; Maina, NH; Gomes, AM; Pinto, EObjective: To develop a semi-quantitative FFQ and to evaluate its validity and reproducibility for the assessment of total dietary intake of Kenyan urban adult population, given its non-existence in Kenya. Design: The current study adopted a cross-sectional design. A culture-sensitive semi-quantitative FFQ was developed and its validity was tested relative to three non-consecutive 24-h recalls (24hR). Reproduci...
A novel strategy to incorporate coconut oil in dairy matrices
Machado, M; Seabra, CL; Rodríguez-Alcalá, L; Gomes, AM; Pintado, M
New combined CFH/MCP mutations and a rare clinical course in atypical haemolyti...
Lopes, D; Gomes, AM; Cunha, C; Pinto, CS; Fidalgo, T; Fernandes, JCAtypical haemolytic uraemic syndrome (aHUS) is a rare, life-threatening, chronic, genetic disease due to uncontrolled alternative pathway complement activation. In this report, we discuss the case of a heterozygous carrier of a mutation on both factor H and membrane cofactor protein, who persistently presents haemolytic anaemia without need for blood transfusions, normal platelet count, normal renal function an...
Adult B-Cell Acute Lymphoblastic Leukemia Cells Display Decreased PTEN Activity...
Gomes, AM; Soares, M; Ribeiro, P; Caldas, J; Póvoa, V; Martins, L; Melão, A; Serra-Caetano, A; Botelho de Sousa, A; Lacerda, J; Barata, JAdult B-cell acute lymphoblastic leukemia remains a major therapeutic challenge, requiring a better characterization of the molecular determinants underlying disease progression and resistance to treatment. Here, using a phospho-flow cytometry approach we show that adult diagnostic B-cell acute lymphoblastic leukemia specimens display PI3K/Akt pathway hyperactivation, irrespective of their BCR-ABL status and de...