18 documents found, page 1 of 2

Intervenção psicológica em crise: respostas psicossociais precoces a vítimas de...

Vivemos numa era em que os acidentes de viação se destacam como sendo uma das maiores preocupações de saúde pública e geradores de trauma, provocando um impacto significativo na saúde mental das vítimas (OPP, 2015). As vítimas de acidentes de viação, ao contrário do que é habitualmente considerado, vão para além dos indivíduos que são diretamente afetados pelo incidente (vítimas primárias), podendo também ser t...

A importância do fornecimento externo de embalagens: estudo de caso

Comparative cost-effectiveness analysis of SARS-CoV-2 Testing Strategy

Whole-genome sequencing as a tool for studying the microevolution of drug-resis...

Treatment of drug-resistant tuberculosis requires extended use of more toxic and less effective drugs and may result in retreatment cases due to failure, abandonment or disease recurrence. It is therefore important to understand the evolutionary process of drug resistance in Mycobacterium tuberculosis. We here in describe the microevolution of drug resistance in serial isolates from six previously treated patie...

The role of extracellular vesicles during CNS development

With a diverse set of neuronal and glial cell populations, Central Nervous System (CNS) has one of the most complex structures in the body. Intercellular communication is therefore highly important to coordinate cell-to-cell interactions. Besides electrical and chemical messengers, CNS cells also benefit from another communication route, what is known as extracellular vesicles, to harmonize their interactions. ...

Formação dos elementos das equipas

Extracellular vesicles in CNS developmental disorders

The central nervous system (CNS) is the most complex structure in the body, consisting of multiple cell types with distinct morphology and function. Development of the neuronal circuit and its function rely on a continuous crosstalk between neurons and non-neural cells. It has been widely accepted that extracellular vesicles (EVs), mainly exosomes, are effective entities responsible for intercellular CNS commun...

Modeling Rett syndrome with human patient-specific forebrain organoids

Engineering brain organoids from human induced pluripotent stem cells (hiPSCs) is a powerful tool for modeling brain development and neurological disorders. Rett syndrome (RTT), a rare neurodevelopmental disorder, can greatly benefit from this technology, since it affects multiple neuronal subtypes in forebrain sub-regions. We have established dorsal and ventral forebrain organoids from control and RTT patient-...

Triagem em Pediatria uma Opção: Canadian Pediatric Triage and Acuity Scale

Os Enfermeiros da Unidade de Urgência Pediátrica sentiram necessidade de aprofundar conhecimentos sobre triagem pediátrica, especificamente sobre a Canadian Pediatric Triage and Acuity Scale (CPTAS) para compre-ender a metodologia deste sistema de triagem; conhecer os seus pressupostos; reconhecer a pertinência do recurso a modificadores de 1.ª e 2.ª ordem na triagem em pediatria; identificar as especificidades...

Prevalence of complications of diabetes mellitus in patients in the Santo Tirso...

Objectives: To estimate the prevalence of complications of diabetes in patients treated in the Santo Tirso/Trofa Group of Health Centers. Study type: A cross-sectional study. Setting: Santo Tirso/Trofa Group of Health Centers. Participants: Type 1 and 2 diabetic patients. Methods: A sample of the type 1 and 2 diabetic patients was randomly selected from the population registered in the health units of the Group...