The influence of metal ions on the photochemical, photophysical, and antibacterial properties of three cationic porphyrin-triphenylphosphonium conjugates was investigated for the first time. Coordination with Zn(II), Pd(II) and Co(II) enabled fine-tuning of these conjugates properties, with Zn(II) complexes demonstrating particular promise. While Pd(II) and Co(II) complexes failed to generate singlet oxygen (1O...
Clear aligners are a modern orthodontic solution designed to address dental malocclusions discreetly and effectively. In terms of clinical side effects, the most reported issues among aligner users are mild irritation of the oral mucosa, localized inflammation, and hypersensitivity. The use of advanced polymer materials in clear aligners, such as polyurethane and PET-G, has gained widespread acceptance due to t...
Background: Inflammatory Bowel Disease (IBD), a chronic condition characterized by gastrointestinal inflammation, is influenced by genetic and environmental factors. Emerging evidence suggests a “mouth-gut axis,” with the oral cavity reflecting extra-intestinal manifestations of IBD. This study evaluated the oral health status of IBD patients and the potential of salivary calprotectin (SCP) as a biomarker for a...
White spot lesions (WSLs) are early clinical stages of enamel demineralization, often related to orthodontic treatment or poor oral hygiene. The use of gels such as fluoride for topical application inhibits demineralization and promotes remineralization of dental tissues through various mechanisms. A variety of therapeutic approaches are available; however, recent research indicates that combined treatment stra...
Cancer stands as the second leading global cause of death, following heart disease. Considering the severe side effects revealed by some chemotherapeutics for tumor treatment and anticancer therapies, the scientific community is actively exploring more effective alternatives. Photodynamic Therapy (PDT) mediated by porphyrin-based photosensitizers (PS) has emerged as an attractive alternative to more conventiona...
Extra virgin olive oil (EVOO) with a high content of polyphenols has attracted attention due to its proved beneficial effects in decreasing the risk of cardiovascular disease, modulating cholesterol levels (HDL and LDL), modulating inflammatory markers, and decreasing the levels of haemoglobin1Ac, suggesting that EVOO can have an impact in glycemia regulation. This study assessed the impact of the consumption o...
The use of advanced polymer materials in clear aligners, such as polyurethane and PET-G, has gained widespread acceptance due to their mechanical properties, biocompatibility and aesthetic appeal. However, concerns persist regarding their potential to release chemical compounds. Our goal is to understand the impact of the toxicity of clear aligners on oral cavity of orthodontic patients. An extensive systematic...
The aim of this study was to perform a systematic review to comprehensively explore the factors contributing to the resin-matrix composites′ toxicity in patients. A systematic review was performed according to the PRISMA guidelines. The bibliographic review was performed in the following databases: PubMed, Cochrane Central and Web of Science. Inclusion and exclusion criteria were established to retrieve article...
Thermal waters (TW) have been valued since ancient times for their unique properties. Sulfurous TW treat dermatological conditions and respiratory infections, while chlorinated TW aid healing, bone health, and digestive function through anti-inflammatory and antiseptic effects. Despite limited studies on TW, research highlights their antioxidant, anti-allergic, and anti-inflammatory effects, including reducing ...