In a context where plastic is often negatively perceived for its environmental impact, there’s a noticeable trend towards replacing it with alternatives like paper or composites. However, these transitions often occur without thorough assessment, potentially leading to the development of new products that may not be environmentally beneficial. Ecodesign emerges as a key solution for sustainability. This researc...
Urban spatial organization provided an important contribution for healthy tourism in the first COVID-19 pandemic period. The 15-Minute City concept promotes walking which is essential for the development of outdoor activities for a healthier tourism. The tourist city of Lagos (Portugal) is a pilot city of the Interreg Med SuSTowns Project which aims to promote sustainable and resilient territories. This study p...
Introduction: Information about pan-genotypic treatments for hepatitis in Portugal is scarce. We aimed to evaluate the effectiveness and safety of glecaprevir plus pibrentasvir (GLE/PIB) treatment for hepatitis C virus (HCV) infection in real-world clinical practice.Methods: An observational prospective study was implemented in six hospitals with 121 adult HCV patients who initiated treatment with GLE/PIB betwe...
O presente relatório surge no termino do Curso de Técnico Superior Profissional em Manutenção e Reparação Automóvel, na Escola Superior de Tecnologia e Gestão do Instituto Politécnico da Guarda. Este estágio teve a duração de 750 horas, o que equivale a aproximadamente quatro meses e meio, foi realizado na oficina Penetras Assistência Auto com início a 28 de fevereiro e fim a 14 de julho de 2022. Com a conclusã...
Modular timber construction embodies a pioneering and eco-friendly methodology within the building sector. With the notable progress made in manufacturing technologies and the advent of engineered wood products, timber has evolved into a promising substitute for conventional materials such as concrete, masonry, and steel. Beyond its structural attributes, timber brings environmental advantages, including its in...
Immune organ failure is frequent in critical illness independent of its cause and has been acknowledged for a long time. Most patients admitted to the ICU, whether featuring infection, trauma, or other tissue injury, have high levels of alarmins expression in tissues or systemically which then activate innate and adaptive responses. Although necessary, this response is frequently maladaptive and leads to organ ...
XLA patient with 7-month course of COVID-19 with persistent plasma SARS-CoV-2 load revealed a sustained non-inflammatory profile of myeloid cells in association with contained severity of disease, arguing in favor of the use of BTK inhibitors in SARS-COV-2 infection.
This document was prepared by the College of Orthopedics of the Portuguese Medical Association with the aim of developing the guidelines on the resumption of elective surgical activity in Orthopedics during the COVID-19 pandemic. It sets the criteria that allow the prioritization of surgeries according to the severity of the clinical situation, based on existing and published classifications. Moreover, it provi...
Accelerate lung repair in SARS-CoV-2 pneumonia is essential for pandemic handling. Innate lymphoid cells (ILCs) are likely players, given their role in mucosal protection and tissue homeostasis. We studied ILC subpopulations at two time points in a cohort of patients admitted in the hospital due to SARS-CoV-2 infection. COVID-19 patients with moderate/severe respiratory failure featured profound depletion of ci...
Este documento foi elaborado pelo Colégio de Ortopedia da Ordem dos Médicos com o objetivo de estabelecer as orientações sobre a retoma da atividade cirúrgica programada em Ortopedia durante a pandemia COVID-19. As presentes normas de orientação: a) definem os critérios que permitem a priorização das cirurgias de acordo com a gravidade da situação clínica, com base em classificações existentes e publicadas; b) ...