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Cultural aspects in breastfeeding in Chinese women: a scoping review

Gomes, Daniela; Martins, Marta Filipa Dias; Magalhães, Rita; Matela, Sandra; Silva, Teresa

Introdution: WHO recommends exclusive breastfeeding until the baby is six months old. Breastfeeding is influenced by various factors, including culture. The Chinese population is part of the Portuguese community; therefore, it is important to understand the reality of this culture regarding breastfeeding, contributing to the optimization of care provision and the promotion of breastfeeding. Aims: Identifying in...

Date: 2025   |   Origin: Cadernos de Saúde

Innovative approaches to polyphenol synthesis: combinatorial biosynthesis unvei...

Rodrigues, Joana Lúcia Lima Correia; Costa, João Manuel Rainha; Gomes, Daniela; Antas, Carolina; Rodrigues, L. R.

Polyphenols, naturally present in plants, are recognized for their biological properties, including antioxidant, anti-inflammatory, anticancer, and estrogenic effects. Their remarkable potential positions polyphenols as promising candidates for therapeutic applications, driving a rapidly expanding market projected to reach $3.5 billion by 2032. However, polyphenols accumulate in low amounts over extended growth...


Baby-Led weaning como método de alimentação complementar: revisão de literatura

Gomes, Daniela; Festas, Constança

Enquadramento: As experiências nutricionais durante a infância e os primeiros anos de vida podem influenciar o desenvolvimento de hábitos alimentares saudáveis. O Baby-Led Weaning (BLW) é um método alternativo de alimentação complementar em que as crianças comem sozinhas, com as mãos, alimentos moídos, picados ou em forma de finger foods. Surgiu como uma alternativa ao método tradicional de alimentação compleme...


De novo curcuminoids production in engineered Escherichia coli

Rodrigues, Joana Lúcia Lima Correia; Antas, Carolina; Gomes, Daniela; Rodrigues, L. R.

Curcuminoids are a mixture of polyphenolic compounds (curcumin, bisdemethoxycurcumin and demethoxycurcumin) produced in the plant Curcuma longa with several therapeutic properties, including anticancer, anti-inflammatory, among others. Given this great potential, the curcuminoids market size is expected to reach $369M by 2033 with 11.3% CAGR [1]. However, these compounds are present in low amounts, accumulate d...


Adverse Drug Reactions and Potentially Inappropriate Medication in Older Patien...

Gomes, Daniela; Herdeiro, Maria; Ribeiro-Vaz, Inês; Ferreira, Pedro; Roque, Fátima

Criteria have been developed to identify potentially inappropriate medications that can enhance adverse reactions, highly prevalent in older patient's therapy. This study aimed to identify potentially inappropriate medications within the adverse drug reactions reported in the Portuguese pharmacovigilance system, characterizing the reports where inappropriate medications were identified. INFARMED, I.P. provided ...


Perspectives on the design of microbial cell factories to produce prenylflavonoids

Gomes, Daniela; Rodrigues, L. R.; Rodrigues, Joana Lúcia Lima Correia

Prenylflavonoids are flavonoid-derived compounds characterized by the presence of a lipophilic prenylated side-chain in the flavonoid skeleton. These compounds are present in several food supplements and food products, and have a wide variety of recognized biological activities, namely estrogenic, antioxidant, anti-inflammatory and anticancer. Since these compounds are present in nature in very low amounts, the...


FoSynBio: Synthetic biology approaches to design and construct microbial cell f...

Braga, Adelaide Correia; Gomes, Daniela; Costa, João Manuel Rainha; Amorim, Cláudia; Cardoso, Beatriz B.; Silvério, Sara Isabel Cruz


Zymomonas mobilis as an emerging biotechnological chassis for the production of...

Braga, Adelaide; Gomes, Daniela; Costa, João Manuel Rainha; Amorim, Cláudia; Cardoso, Beatriz; Gudiña, Eduardo José; Silvério, Sara Isabel Cruz

Zymomonas mobilis is a well-recognized ethanologenic bacterium with outstanding characteristics which make it a promising platform for the biotechnological production of relevant building blocks and fine chemicals compounds. In the last years, research has been focused on the physiological, genetic, and metabolic engineering strategies aiming at expanding Z. mobilis ability to metabolize lignocellulosic substra...


Engineering Zymomonas mobilis to produce tailor-made fructooligosaccharides

Braga, Adelaide; Gomes, Daniela; Amorim, Cláudia; Cardoso, B.; Silvério, Sara Isabel Cruz; Rodrigues, Joana Lúcia Lima Correia; Rodrigues, L. R.

[Excerpt] Background: Fructooligosaccharides (FOS) are promising prebiotics in the increasing market of functional food. Industrially, these compounds are produced from sucrose using fructosyltransferase (Ftase) or β-fructofuranosidase enzymes (Ffase) [1]. Although it is known that these compounds may have a great impact in health, it has also been described that the beneficial effects may depend on the relativ...


Zymomonas mobilis: a promising microorganism for prebiotic production

Braga, Adelaide; Gomes, Daniela; Rainha, João; Amorim, Cláudia Catarina Oliveira; Cardoso, B.; Gudiña, Eduardo José; Silvério, Sara Isabel Cruz

Zymomonas mobilis (ZM) is an ethanologenic bacterium with outstanding characteristics which makes it an interesting chassis for the biotechnological production of prebiotics. Fructooligosaccharides (FOS) are promising prebiotics in the increasing market of functional food. In this work, a Box-Behnken design approach was used to optimize the medium composition and maximize the FOS content. Under optimal conditio...


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