2 documents found, page 1 of 1
Drosophila motor neuron boutons remodel through membrane blebbing coupled with ...
Fernandes, Andreia R.; Martins, João P.; Gomes, Edgar R.; S. Mendes, César; Teodoro, RitaFunding Information: We would like to thank Telmo Pereira from the Microscopy Facility for technical support, the Fly Facility at Nova Medical Research; CONGENTO: consortium for genetically tractable organisms. We thank the Developmental Studies Hybridoma Bank, Bloomington Drosophila Stock Center and VDRC for antibodies and fly stocks. This work was supported by PTDC-01778/2022- NeuroDev3D to R.O.T. GEMiNI and ...
Calpains are activated by photodynamic therapy but do not contribute to apoptot...
Almeida, Ramiro D.; Gomes, Edgar R.; Carvalho, Arsélio P.; Duarte, Carlos B.Photodynamic therapy (PDT) of cancer is a promising technique based on the formation of singlet oxygen following irradiation of a sensitizer with visible light. In the present work we investigated the role of calpains in PDT, using the human lymphoblastoid CCRF-CEM cells and bisulfonated aluminum phthalocyanine (AlPcS2) as a sensitizer. Photosensitization induced apoptotic cell death and a time-dependent activa...