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What determines health professionals COVID-19 vaccine hesitancy? A nationwide s...

Estrela, Marta; Silva, Tânia M; Roque, Vítor; Gomes, Eva Rebelo; Roque, Fátima; Herdeiro, Maria Teresa; Figueiras, Adolfo

Introduction: To contain the COVID-19 pandemic, higher vaccination rates are essential. However, as vaccine hesitancy is a reality, it is important to understand what drives health professionals to refuse getting vaccinated against COVID-19, who have been in the frontline of this pandemic since its beginning and may be key actors to improve vaccine coverage among their patients. Purpose: This study aims to asse...


Chronic spontaneous urticaria in pediatric age

Cunha, Inês Machado; Gomes, Eva Rebelo

Introduction: Chronic spontaneous urticaria is characterized by emergence of pruritic maculopapular cutaneous lesions recurring for more than six weeks, without known triggering factor. Association with autoimmunity is sometimes present, with urticaria preceding the onset of autoimmune disease. Clinical case: A five-year-old female with a personal history of allergic asthma and family history of thyroid disease...


Anaphylaxis in pediatric age: an overview

Marques, Maria Luís; Gouveia, Joana; Cunha, Inês Machado; Gomes, Eva Rebelo

Anaphylaxis is defined as an acute severe, life-threatening hypersensitivity reaction. The condition’s real prevalence and incidence are difficult to estimate, but seem to be increasing, particularly in children. Anaphylaxis clinical presentation varies according to age and other individual factors. Although consensual clinical criteria exist, including in pediatric age, diagnosis can be challenging. Food aller...


Anaphylaxis in pediatric age: an overview

Marques, Maria Luís; Gouveia, Joana; Cunha, Inês Machado; Gomes, Eva Rebelo

Anaphylaxis is defined as an acute severe, life-threatening hypersensitivity reaction. The condition’s real prevalence and incidence are difficult to estimate, but seem to be increasing, particularly in children. Anaphylaxis clinical presentation varies according to age and other individual factors. Although consensual clinical criteria exist, including in pediatric age, diagnosis can be challenging. Food aller...


Hipersensibilidade medicamentosa em crianças de idade pré-escolar

Viana, Jorge Da Costa; Abreu, Carmo; Gomes, Eva Rebelo

Introdução: As reações de hipersensibilidade medicamentosa (RHM) são reacções adversas reprodutíveis que se caracterizam por sintomas típicos de alergia que surgem após administração de doses terapêuticas habituais. A sua prevalência em idade pediátrica atinge os 10%. A investigação das RHM inclui a realização de testes cutâneos, pesquisa de imunoglobulinas específicas para os alergénios implicados e provas de ...


Hipersensibilidade medicamentosa em crianças de idade pré-escolar

Viana, Jorge da Costa; Abreu, Carmo; Gomes, Eva Rebelo

Introdução: As reações de hipersensibilidade medicamen¬tosa (RHM) são reacções adversas reprodutíveis que se carac¬terizam por sintomas típicos de alergia que surgem após admi-nistração de doses terapêuticas habituais. A sua prevalência em idade pediátrica atinge os 10%. A investigação das RHM inclui a realização de testes cutâneos, pesquisa de imunoglobulinas específicas para os alergénios implicados e provas ...


Perfluorocarbon compounds used as oxygen carriers: from liquid ventilation to b...

Gomes, Lígia Rebelo; Gomes, Eva Rebelo

Perfluorocarbon compounds are fluorine substituted hydrocarbons. They exhibit unique properties due to the specificity of the carbon –fluorine linkage. Among these, the high gas solubility and the low surface tension are the most interesting characteristics for their use in clinic. There are several biological fields of potential applications of perfluorocarbons. Concerning the clinical applications for perfluo...


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