4 documents found, page 1 of 1
Capacitated waste collection problem solution using an open-source tool
Silva, Adriano Santos; Alves, Filipe; Diaz de Tuesta, José Luis; Rocha, Ana Maria A. C.; Pereira, Ana I.; Silva, Adrián M. T.; Gomes, Helder T.Population in cities is growing worldwide, which puts the systems that offer basic services to citizens under pressure. Among these systems, the Municipal Solid Waste Management System (MSWMS) is also affected. Waste collection and transportation is the first task in an MSWMS, carried out traditionally in most cases. This approach leads to inefficient resource and time expense since routes are prescheduled or d...
A tailor-made protocol to synthesize yolk-shell graphene-based magnetic nanopar...
Rodrigues, Raquel O.; Baldi, Giovanni; Doumett, Saer; Gallo, Juan; Bañobre-López, Manuel; Dražić, Goran; Calhelha, Ricardo C.; Ferreira, Isabel C. F. R.A simple tailor-made protocol to synthesize graphene-based magnetic nanoparticles (GbMNPs) for nanomedicine is herein reported. Different GbMNPs with very distinctive physicochemical and toxicological properties were synthesized by adjusting the number of carbon precursors in the coating of superparamagnetic iron oxide nanoparticles. In vitro tests show the ability to use these GbMNPs as intelligent and on-dema...
Multifunctional graphene-based magnetic nanocarriers for combined hyperthermia ...
Rodrigues, Raquel O.; Baldi, Giovanni; Doumett, Saer; Garcia-Hevia, Lorena; Gallo, Juan; Bañobre-López, Manuel; Dražić, Goran; Calhelha, Ricardo C.The synthesis of hydrophilic graphene-based yolk-shell magnetic nanoparticles functionalized with copolymer pluronic F-127 (GYSMNP@PF127) is herein reported to achieve an efficient multifunctional biomedical system for mild hyperthermia and stimuli-responsive drug delivery. In vitro tests revealed the extraordinary ability of GYSMNP@PF127 to act as smart stimuli-responsive multifunctional nanomedicine platform ...
Haemocompatibility of iron oxide nanoparticles synthesized for theranostic appl...
Rodrigues, Raquel O.; Bañobre-López, Manuel; Gallo, Juan; Tavares, P. B.; Silva, Adrián M. T.; Lima, Rui Alberto Madeira Macedo; Gomes, Helder T.The poor heating efficiency of the most reported magnetic nanoparticles (MNPs), allied to the lack of comprehensive biocompatibility and haemodynamic studies, hampers the spread of multifunctional nanoparticles as the next generation of therapeutic bio-agents in medicine. The present work reports the synthesis and characterization, with special focus on biological/toxicological compatibility, of superparamagnet...