Made available in DSpace on 2021-06-25T10:13:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-09-01; Leaf-cutting ants of the genus Atta are considered one of the main forest and agricultural pests. Currently, chemical control using granulated baits is considered the most efficient, however, with the inadequate adoption of management it can harm non-target organisms and the agro-ecosystem. Phorid paras...
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Wharton's jelly stem cells (WJSCs) are a potential source of transplantable stem cells in cartilage-regenerative strategies, due to their highly proliferative and multilineage differentiation capacity. We hypothesized that a non-direct co-culture system with human articular chondrocytes (hACs) could enhance the potential chondrogenic phenotype of hWJSCs during the expansion phase compared to those expanded in m...
The present work focuses on a specific challenge of great clinical importance: targeted therapy for osteoarthritis (OA). The identification of molecules expressed exclusively, or at elevated levels, by cartilage cells (chondrocytes) in OA conditions might provide a strategy for targeted OA therapy by enhancing drug specificity. Towards this goal, we report the identification of peptide ligands, that bind select...
Platelet-rich plasma (PRP), a cocktail of platelet growth factors and bioactive proteins, has been proposed as a therapeutic agent to restore damaged articular cartilage. We report the biological effect of the platelet lysate (PL), a PRP derivative, on primary human articular chondrocytes cultured under both physiological and inflammatory conditions. When added to the culture medium, PL induced a strong mitogen...
p.1-16; Submitted by Bruna Lessa (lessbruna@gmail.com) on 2012-07-06T20:10:25Z No. of bitstreams: 1 (111).pdf: 577860 bytes, checksum: 36c90a00d352a0c2435ea36e130abaed (MD5); Made available in DSpace on 2012-07-06T20:10:25Z (GMT). No. of bitstreams: 1 (111).pdf: 577860 bytes, checksum: 36c90a00d352a0c2435ea36e130abaed (MD5) Previous issue date: 2009; We consider the Euclidean D-dimensional N-component 4 0 model...
cartilage. We report the biological effect of the platelet lysate (PL), a PRP derivative, on primary human articular chondrocytes (HAC) cultured under both physiological and inflammatory condition. Added to the culture medium, PL induced a strong mitogenic response in the chondrocytes. The in vitro expanded cell population maintained a chondrogenic re-‐differentiation potential as revealed by micromass culture...
[Excerpt] Cartilage tissue loss, as a result of trauma, congenital disorders and diseases of joints, involving structural damage of articular cartilage surface, is a substantial clinical problem representing a major challenge for cartilage tissue engineering. The aim of our study was to evaluate the in vitro and in vivo behavior of human articular chondrocytes encapsulated within a novel carrageenan in situ inj...