3 documents found, page 1 of 1
Doxycycline induces bone repair and changes in Wnt signalling
Gomes, Kátia do Nascimento; Alves, Ana Paula Negreiros Nunes; Dutra, Paula Góes Pinheiro; Viana, Glauce Socorro de BarrosDoxycycline (DOX) exhibits anti-in fl ammatory and MMP inhibitory properties. The objectives of this study were to evaluate the effects of DOX on alveolar bone repair. Controls (CTL) and DOX-treated (10 and 25 mg . kg − 1 ) molars were extracted, and rats were killed 7 or 14 days later. The maxillae were processed and subjected to histological and immunohistochemical assays. Hematoxylin-eosin staining (7th day)...
Avaliação do efeito da Doxiciclina associada ou não à decametasone no modelo de...
Gomes, Kátia do NascimentoThe alveolar bone repair model, through dental excision in rats, allows the longitudinal study of local and systemic parameters. This allows learning the pathophysiology in inflammatory bone remodeling process. The objective of the research was to investigate the effect of doxycycline associated or not with dexamethasone on the events that follow the bone reabsorption process in alveolar bone repair in rats. Th...
Modelo experimental de disfunção temporomandibular em ratos
Gomes, Kátia do NascimentoStudies on rats spontaneous behaviors and pharmacological effects of drugs on them, as well as their body weight and histopathological analysis of their joints were carried out to investigate the effect of chronic inflammation of the temporomandibular articulation induced by the administration of Complete Freund Adjuvant (CFA) compared with the acute and subacute stimulus of 2.5% formalin. After CFA, 2.5% forma...