4 documents found, page 1 of 1
Blades and barriers: Oral vaccines for conquering cancers and warding off infec...
Yang, K.; Liu, J.; Zhao, Y.; Xu, H.; Zu, M.; Li, B.; Shi, X.; Reis, R. L.; Kundu, Subhas C; Xiao, B.Global public health faces substantial challenges from malignant tumors and infectious diseases. Vaccination provides an approach for treating and preventing these diseases. Oral vaccinations are particularly advantageous in disease treatment and prevention due to their non-invasive nature, high patient compliance, convenience, cost-effectiveness, and capacity to stimulate comprehensive and adaptive immune resp...
Photoactive cationic conjugated microporous polymers containing pyrimidine with...
Liu, G.; Bao, S.; Shi, J.; Xie, C.; Liao, F.; Wang, L.; Zheng, F.; Reis, R. L.; Kundu, Subhas C; Xiao, B.; Yang, X.; Duan, L.Pathogenic bacterial invasion leads to severe inflammation that hinders wound healing, and it has become a major medical threat worldwide. Photodynamic therapy (PDT) has emerged as a promising strategy for treating microbial infection; however, developing a dressing with PDT effect and excellent biological functions poses a formidable challenge. Herein, a novel cationic pyrimidine-modified conjugated microporou...
Flying-saucer-shaped nanoheterojunctions with enhanced colorectal tumor accumul...
Ma, Y.; Cao, Y.; Zu, M.; Gao, Q.; Liu, G.; Ji, J.; Xu, H.; Yang, Q.; Shi, X.; Reis, R. L.; Kundu, Subhas C; Zheng, J.; Li, Z.; Xiao, B.The treatment outcomes of nanomedicines against colorectal cancer are severely restricted by their insufficient accumulation in the tumor tissues, unsatisfactory antitumor effect, and weak immunometabolic modulation. To address these issues, flying-saucer-shaped nanoheterojunctions by coating copper oxide (CuxO) onto the surface of PEGylated zinc oxide (ZnO) nanoparticles are constructed. When exposed to ultras...
Facilely printed silk fibroin hydrogel microparticles as injectable long-lastin...
Xie, C. Y.; Yang, X.; Zheng, F.; Shi, J. H.; Huo, C. X.; Wang, Z. Y.; Reis, R. L.; Kundu, Subhas C; Xiao, B.; Duan, L.There is a high demand from aging people for facial fillers with desirable biocompatibility and lasting filling effects to overcome facial depression. Novel injectable regenerated silk fibroin (RSF) microparticles were facilely printed from a glycidyl methacrylate-modified silk fibroin hydrogel to address this issue. The β-sheet content and mechanical properties of the RSF hydrogel can be simply modulated by t...