5 documents found, page 1 of 1
Modelling the epidemiology of residual Plasmodium vivax malaria in a heterogene...
Gomes, Maria Gabriela Miranda
A systematic review of East African-Indian family of Mycobacterium tuberculosis...
Duarte, Tonya Azevedo; Nery, Joilda Silva; Boechat, Neio; Pereira, Susan Martins; Simonsen, Vera; Oliveira, Martha; Gomes, Maria Gabriela MirandaThe Mycobacterium tuberculosis East African-Indian (EAI) spoligotyping family (belonging to lineage 1, Indo-Oceanic, defined by the region of deletion RD239) is distributed worldwide, but is more prevalent in Southeast Asia, India, and East Africa. Studies in Latin America have rarely identified EAI. In this study, we describe the occurrence of the EAI family in Brazil.
SNP typing reveals similarity in Mycobacterium tuberculosis genetic diversity b...
Marques, Isabel; Soares, Patricia; Nebenzahl-Guimaraes, Hanna; Costa, Joao; Miranda, Anabela; Duarte, Raquel; Alves, Adriana; Macedo, RitaHuman tuberculosis is an infectious disease caused by bacteria from the Mycobacterium tuberculosis complex (MTBC). Although spoligotyping and MIRU-VNTR are standard methodologies in MTBC genetic epidemiology, recent studies suggest that Single Nucleotide Polymorphisms (SNP) are advantageous in phylogenetics and strain group/lineages identification. In this work we use a set of 79 SNPs to characterize 1987 MTBC ...
SNP typing reveals similarity in Mycobacterium tuberculosis genetic diversity b...
Lopes, João S.; Marques, Isabel; Soares, Patricia; Nebenzahl-Guimaraes, Hanna; Costa, João; Miranda, Anabela; Duarte, Raquel; Alves, AdrianaHuman tuberculosis is an infectious disease caused by bacteria from the Mycobacterium tuberculosis complex (MTBC). Although spoligotyping and MIRU-VNTR are standard methodologies in MTBC genetic epidemiology, recent studies suggest that Single Nucleotide Polymorphisms (SNP) are advantageous in phylogenetics and strain group/lineages identification. In this work we use a set of 79 SNPs to characterize 1987 MTBC ...
Pertussis: increasing disease as a consequence of reducing transmission
Gomes, Maria Gabriela Miranda; Águas, R.; Gonçalves, G.Since the 1980s, the occurrence of pertussis cases in developed countries has increased and shifted towards older age groups. This resurgence follows 30 years of intense mass vaccination, and has been attributed primarily to three factors: (1) more effective diagnosis of the disease, (2) waning of vaccine-induced immunity, and (3) loss of vaccine efficacy due to the emergence of new Bordetella pertussis strains...