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Transcriptomic and metabolomic profiling of ionic liquid stimuli unveils enhanc...

Alves, Paula C.; Hartmann, Diego O.; Núñez, Oscar; Martins, Isabel; Gomes, Teresa L.; Garcia, Helga; Galceran, Maria Teresa; Hampson, Richard

The inherent potential of filamentous fungi, especially of Ascomycota, for producing diverse bioactive metabolites remains largely silent under standard laboratory culture conditions. Innumerable strategies have been described to trigger their production, one of the simplest being manipulation of the growth media composition. Supplementing media with ionic liquids surprisingly enhanced the diversity of extracel...


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