Summary Fusion peptides inspired by natural elastomeric proteins are fused to a keratin peptide (KP) and tested on damaged hair. Here, we report thermal and mechanical tests conducted on treated damaged hair in conjunction with the peptides physicochemical properties, resulting in a statistical multiparametric analysis. Among the parameters, the Youngs modulus and the keratin helix denaturation temperature show...
SARS-CoV-2 infection can be followed by several cardiovascular complications such as pulmonary thromboembolism, myocardial injury and pericarditis.This case refers to a 48-year-old man with a one year history of unstable angina who presented to the emergency department with chest pain, dyspnea, dry cough and fever. He was admitted with the diagnosis of pulmonary thromboembolism associated with pulmonary infarct...
Thrombotic microangiopathies (TMA) are rare diseases,with high morbimortality. Among them, atypical hemolytic uremic syndrome (HUS), associated with deregulation of alternative complement pathway (genetic/acquired), represents a diagnostic challenge. Characterized by thrombotic microangiopathy, acute renal failure is one of its main features. Etiological/ precipitant detection (TMA triggers) is essential, even ...
Paragangliomas are rare neuroendocrine tumors that arise from the extra-adrenal sympathetic and parasympathetic paraganglia. Most parasympathetic paragangliomas are nonfunctional, derived from non-chromaffin cells located in the neck and at the base of the skull. It is often necessary to exclude it in patients with early and severe arterial hypertension, or with therapeutic refractoriness. This case shows an ex...
We present a 39-year-old male, previous smoker, with no other known cardiovascular risk factors. He was referred to Internal Medicine for study of thrombophilia, because of repeated deep vein thrombosis. Multiple diagnostic tests were undertaken where HbA1c assay was included. The result was 14.6%. The patient did not have a prior diagnosis of diabetes and denied any symptoms. Fasting blood glucose and blood co...
Aim: To verify if intensive antihypertensive treatment (systolic blood pressure; Objetivo: Verificar se o efeito do tratamento anti-hipertensor intensivo (pressão arterial sistólica
The synthesis of a highly water soluble 3-hydroxy-4-pyridinone ligand, functionalized with a hydrophilic ethylene glycol chain (PEG-HPO), was successfully achieved and is reported together with that of its iron (III) complex. The improved hydrophilicity of both the PEGylated 3,4-HPO ligand and its iron(III) complex were fully investigated in an analytical application and, the new chelator is proposed for the sp...
BACKGROUND: An autoimmune disease is characterized by tissue damage, caused by self-reactivity of different effector mechanisms of the immune system, namely antibodies and T cells. All autoimmune diseases, to some extent, have implications for fertility and obstetrics. Currently, due to available treatments and specialised care for pregnant women with autoimmune disease, the prognosis for both mother and child ...
Orientador: João de Fernandes Teixeira; Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Educação; Resumo: O objeto de nossa investigação é a questão da consciência e sua temporalidade interna, aplicada ao problema do pensamento em autômatos. Iniciamos pela insuficiência do cogito cartesiano como fundamento para o reconhecimento da consciência do outro, considerando o critério comportamental e...