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Does smoking habit affect dendritic cell expression in oral squamous cell carci...
Barbieri,Silene; Schuch,Lauren Frenzel; Cascaes,Andreia Morales; Gomes,Ana Paula Neutzling; Tarquinio,Sandra Beatriz Chaves; Mesquita,Ricardo AlvesAbstract: The aim of this study was to determine the presence of immature CD1a+ and mature CD83+ dendritic cells in oral squamous cell carcinoma, to compare immunoreactivity between smokers and nonsmokers, and to correlate the results with histopathological grading. In this observational study, twenty-eight paraffin-embedded biopsies of oral squamous cell carcinoma were retrospectively retrieved and submitted t...
Demographic and Clinical Profile of Oral Squamous Cell Carcinoma from a Service...
Alves,Alessandro Menna; Correa,Marcos Britto; Silva,Karine Duarte da; Araújo,Lenita Maria Aver de; Vasconcelos,Ana Carolina UchoaAbstract The aim of this study was to evaluate the demographic and clinical profile of the oral squamous cells carcinoma (OSCC) cases registered in a center of oral diagnosis in southern Brazil. Eight hundred and six individuals with OSCC from 1959 to 2012 were included in this study. The variables recorded were: sex, age, occupation according to workplace, alcohol and tobacco consumption, skin color, tumor loc...
Physicochemical and Biological Evaluation of Endodontic Filling Materials for P...
Pilownic,Katerine Jahnecke; Gomes,Ana Paula Neutzling; Wang,Zhe Jun; Almeida,Luiza Helena Silva; Romano,Ana Regina; Shen,YaAbstract This study assessed the pH, radiopacity, antimicrobial effect, cytotoxicity and biocompatibility of endodontic filling materials for primary teeth. Zinc oxide eugenol (ZOE), Vitapex and Calen paste thickened with zinc oxide (ZO) were evaluated in comparison to an experimental MTA-based material. Radiopacity was tested using a graduated aluminum stepwedge with a digital sensor (n=5). The materials pH wa...
Tenascin and Fibronectin Expression after Pulp Capping with Different Hemostati...
Baldissera,Elaine Zanchin; Silva,Adriana Fernandes da; Gomes,Ana Paula Neutzling; Etges,Adriana; Botero,Tatiana; Demarco,Flavio FernandoThis study investigated the expression of extracellular matrix glycoproteins tenascin (TN) and fibronectin (FN) in pulp repair after capping with calcium hydroxide (CH), following different hemostasis protocols. Class I cavities with a pulp exposure were prepared in 42 human third molars scheduled for extraction. Different hemostatic agents (0.9% saline solution, 5.25% sodium hypochlorite and 2% chlorhexidine d...
Pulp Tissue Dissolution Capacity of Sodium Hypochlorite Combined with Cetrimide...
Almeida,Luiza Helena Silva de; Leonardo,Natália Gomes e Silva; Gomes,Ana Paula Neutzling; Giardino,Luciano; Souza,Erick Miranda; Pappen,Fernanda GeraldoThis study evaluated the influence of the addition of cetrimide and polypropylene glycol to sodium hypochlorite (NaOCl) on its capacity to dissolve pulp tissue. Bovine pulp fragments with standardized weight and volume were immersed for 5, 15 and 30 min in 2 mL of NaOCl and Hypoclean (NaOCl added with cetrimide and polypropylene glycol) solutions at 5.25%, 2.5%, 1%, 0.5% and 0.25% and afterwards re-weighted. Di...
Etiologic factors associated with oral squamous cell carcinoma in non-smokers a...
Vargas-Ferreira,Fabiana; Nedel,Fernanda; Etges,Adriana; Gomes,Ana Paula Neutzling; Furuse,Cristiane; Tarquinio,Sandra Beatriz ChavesOral squamous cell carcinoma (OSCC) is the fifth most common type of cancer in the world. The effect of some etiological factors is well established in the literature, such as consumption of tobacco and alcohol. However, approximately 15 to 20% of all oral cancer cases occur in patients without the traditional risk factors, reflecting in numerous cases of OSCC in non-smokers and non-alcoholic drinkers. Also, se...
Diclofenac in hyaluronic acid gel: an alternative treatment for actinic cheilitis
Lima,Giana da Silveira; Silva,Gabriela Ferrari da; Gomes,Ana Paula Neutzling; Araújo,Lenita Maria Aver de; Salum,Fernanda GonçalvesOBJECTIVE: Actinic cheilitis (AC) is a precancerous lesion of the lip vermillion caused by prolonged exposure to ultraviolet light. The aim of this study was to evaluate the effect of 3% diclofenac in 2.5% hyaluronic acid gel in the treatment of AC. METHODS: Thirty-four patients with chronic AC were treated twice a day with topical diclofenac during a period of 30 to 180 days. The individuals were followed up e...
Comparative analysis of the mast cell density in normal oral mucosa, actinic ch...
Gomes,Ana Paula Neutzling; Johann,Julia Elis; Lovato,Gabriela Gularte; Ferreira,Aline MarquesPrevious studies have shown that the number of mast cells is increased in ultraviolet (UV) irradiated skin and in neoplasias. Actinic cheilitis (AC) is a lesion caused by excessive exposure to sunlight that can transform into lip squamous cell carcinoma. The aim of this study was to compare the number of mast cells in 4 groups: NOM = normal oral mucosa (n=6); MDAC = mild dysplasia in actinic cheilitis (n=13); S...
A survey of oral and maxillofacial biopsies in children: a single-center retros...
Lima,Giana da Silveira; Fontes,Silvia Terra; Araújo,Lenita Maria Aver de; Etges,Adriana; Tarquinio,Sandra Beatriz Chaves; Gomes,Ana Paula NeutzlingDespite the large number of published cases about oral and maxillofacial pediatric lesions, the literature is scarce on epidemiological studies regarding the prevalence of these entities. This study retrieved oral and maxillofacial pediatric lesions from the Center of Diagnosis of Oral Diseases (CDDB) at the Dental School of the Federal University of Pelotas (UFPEL), comprising a 20-year period (1983-2002). Fro...