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Unconstrained mining of transcript data reveals increased alternative splicing ...

Mollet, I. G.; Ben-Dov, Claudia; Felício-Silva, Daniel; Grosso, A. R.; Eleutério, Pedro; Alves, Ruben; Staller, Ray; Silva, Tito Santos

Mining massive amounts of transcript data for alternative splicing information is paramount to help understand how the maturation of RNA regulates gene expression. We developed an algorithm to cluster transcript data to annotated genes to detect unannotated splice variants. A higher number of alternatively spliced genes and isoforms were found compared to other alternative splicing databases. Comparison of huma...

Date: 2010   |   Origin: Veritati - Repositório Institucional da Universidade Católica Portuguesa
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