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Exploring silk Sericin for diabetic wounds: an in situ-forming hydrogel to prot...

Baptista-Silva, Sara; Bernardes, Beatriz G.; Borges, Sandra; Rodrigues, Ilda; Fernandes, Rui; Gomes-Guerreiro, Susana; Pinto, Marta Teixeira

Chronic wounds are one of the most frequent complications that are associated with diabetes mellitus. The overproduction of reactive oxygen species (ROS) is a key factor in the delayed healing of a chronic wound. In the present work, we develop a novel in situ-forming silk sericin-based hydrogel (SSH) that is produced by a simple methodology using horseradish peroxidase (HRP) crosslinking as an advanced dressin...


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