4 documents found, page 1 of 1
Ascaris lumbricoides coinfection reduces tissue damage by decreasing IL-6 level...
Santos,João Hugo Abdalla; Bührer-Sékula,Samira; Melo,Gisely Cardoso; Cordeiro-Santos,Marcelo; Pimentel,João Paulo Diniz; Gomes-Silva,AdrianoAbstract INTRODUCTION: Immunological control of Mycobacterium tuberculosis infection is dependent on the cellular immune response, mediated predominantly by Th1 type CD4+ T cells. Polarization of the immune response to Th2 can inhibit the host immune protection against pathogens. Patients with tuberculosis coinfected with helminths demonstrate more severe pulmonary symptoms, a deficiency in the immune response ...
First report of treatment failure in a patient with cutaneous leishmaniasis inf...
Vieira-Gonçalves,Ricardo; Fagundes-Silva,Giselle Aparecida; Heringer,Júlia Furtado; Fantinatti,Maria; Da-Cruz,Alda Maria; Oliveira-Neto,Manoel PaesAbstract We report the case of a 32-year-old man from Rio de Janeiro, who was infected in the Amazon region of Brazil by Leishmania (Viannia) naiffi. Generally, patients with L. naiffi cutaneous leishmaniasis exhibit a good therapeutic response to either pentavalent antimonials or pentamidine. However, after pentamidine treatment, this patient’s infection evolved to therapeutic failure. To understand this clini...
Fatal septic shock caused by Paracoccidioides brasiliensis phylogenetic species...
Macedo,Priscila Marques de; Almeida-Paes,Rodrigo; Almeida,Marcos de Abreu; Coelho,Rowena Alves; Oliveira Filho,Marcio Amaral de; Medeiros,Denise MachadoAbstract The authors report the first case of fatal septic shock, a rare clinical presentation of paracoccidioidomycosis (PCM) caused by Paracoccidioides brasiliensis S1. We also provide an immunological evaluation of the patient. Severe clinical signs such as organ dysfunction and digital gangrene occurred in this case. The patient presented a remarkable cell activation profile and diminished percentage of per...
Serological reactivity of different antigenic preparations of Leishmania (Leish...
Gomes-Silva,Adriano; Souza,Maria Aparecida; Afonso-Cardoso,Sandra Regina; Andrade,Lívia Resende; Dietze,Reynaldo; Lemos,Elenice; Belli,AlejandroTotal antigen from Leishmania (Leishmania) amazonensis and isolates from the Leishmania braziliensis complex, along with their respective antigenic fractions obtained by affinity chromatography on concanavalin-A-Sepharose and jacalin-agarose columns evaluated using immunoenzymatic ELISA assay. For this, serum samples from 229 patients were used, grouped as American tegmental leishmaniasis (nº=58), visceral leis...