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Transcriptomic-Based Classification Identifies Prognostic Subtypes and Therapeu...
Esperança-Martins, Miguel; Vasques, Hugo; Ravasqueira, Manuel Sokolov; Lemos, Maria Manuel; Fonseca, Filipa; Coutinho, Diogo; López, Jorge AntonioFunding Information: This research was sponsored by F.Hoffmann-LaRoche AG and by Foundation Medicine Inc. under the RNA LDT Research Programme. Funding Information: We would like to thank F.Hoffmann-LaRoche AG and Foundation Medicine Inc. for providing the FoundationOneCDx and FoundationOneRNA assays, and for all the technical support, specifically during the transfer of the sequencing data via the safe platfor...
Succinate Dehydrogenase B (SDHB) Overexpression with Enzymatic Dysfunction Defi...
Esperança-Martins, Miguel; Vasques, Hugo; Ravasqueira, Manuel Sokolov; Santos, Filipa; Fonseca, Filipa; Queiroz, António Syder; Boavida, JoãoPublisher Copyright: ©2025 The Authors; Published by the American Association for Cancer Research.; Undifferentiated pleomorphic sarcoma (UPS) remains one of the most clinically aggressive and poorly characterized soft-tissue sarcoma subtypes. To uncover distinctive molecular traits for UPS, a multiomics analysis of UPS compared with leiomyosarcoma (LMS) and liposarcoma (LPS) was performed. Transcriptomic profi...