4 documents found, page 1 of 1
Olive Oil Industry By-Products as a Novel Source of Biophenols with a Promising...
Gonçalves, Marta; Costa, Marlene; Paiva-Martins, Fátima; Silva, PaulaUIDB/05021/2020 UIDP/05021/2020 UIDB/50006/2020; This review explores the potential health benefits and applications of phenolic secoiridoids derived from olive oil by-products in the prevention of Alzheimer’s disease (AD). As reviewed herein, polyphenols, such as epigallocatechin-3-gallate, epicatechin, and resveratrol, show in vitro and in vivo antioxidant, anti-inflammatory, and neuroprotective properties, a...
Olive Oil Components as Novel Antioxidants in Neuroblastoma Treatment
Gonçalves, Marta; Aiello, Anna; Rodríguez-Pérez, María; Accardi, Giulia; Burgos-Ramos, Emma; Silva, PaulaUIDB/05021/2020 UIDP/05021/2020; In this review, we explored the therapeutic potential of oleuropein (OLE) and hydroxytyrosol (HT) in the treatment of neuroblastoma (NB). NB is an extracranial tumour that predominantly affects children aged between 17 and 18 months. Recurrence and drug resistance have emerged as the biggest challenges when treating NB, leading to a crucial need for new therapeutic approaches. F...
A Narrative Review of Metabolomic Insights into Olive Oil’s Nutritional Value
Gonçalves, Marta; Rodríguez-Pérez, María; Calabrò, Anna; Burgos-Ramos, Emma; Accardi, Giulia; Silva, PaulaUIDB/05021/2020 UIDP/05021/2020; This review explores the critical role of advanced metabolomic methodologies in interpreting the complex relationship between the bioactive compounds in olive oil and their health benefits. Olive oil, the cornerstone of the Mediterranean diet, is renowned for its numerous health benefits, including anti-inflammatory, antioxidant, and cardioprotective properties. This review begi...
Neuroprotective Effects of Olive Oil
Gonçalves, Marta; Vale, Nuno; Silva, PaulaUIDB/05021/2020 UIDP/05021/2020; Neurodegenerative diseases are a significant challenge to global healthcare, and oxidative stress plays a crucial role in their development. This paper presents a comprehensive analysis of the neuroprotective potential of olive oil, with a primary focus on its antioxidant properties. The chemical composition of olive oil, including key antioxidants, such as oleuropein, hydroxyty...