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Transcranial Direct Current Stimulation as an Add-on Treatment to Cognitive-Beh...

Carvalho, S; Gonçalves, ÓF; Brunoni, AR; Fernandes-Gonçalves, A; Fregni, F; Leite, J

Background: Major Depressive Disorder (MDD) affects more than 264 million people worldwide. Current treatments include the use of psychotherapy and/or drugs, however ~30% of patients either do not respond to these treatments, or do not tolerate the side effects associated to the use of pharmacological interventions. Thus, it is important to study non-pharmacological interventions targeting mechanisms not direct...

Date: 2020   |   Origin: Saúde - CUF

Patterns of Default Mode Network Deactivation in Obsessive Compulsive Disorder

Gonçalves, ÓF; Soares, JM; Carvalho, S; Leite, J; Ganho-Ávila, A; Fernandes-Gonçalves, A; Pocinho, F; Carracedo, A; Sampaio, A

The objective of the present study was to research the patterns of Default Mode Network (DMN) deactivation in Obsessive Compulsive Disorder (OCD) in the transition between a resting and a non-rest emotional condition. Twenty-seven participants, 15 diagnosed with OCD and 12 healthy controls (HC), underwent a functional neuroimaging paradigm in which DMN brain activation in a resting condition was contrasted with...

Date: 2017   |   Origin: Saúde - CUF

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