5 documents found, page 1 of 1
COVID-19 vaccines effectiveness against symptomatic disease and severe outcomes...
Brazete, C; Brazete, J; Alves, F; Aguiar, A; Gonçalves, AM; Cardoso, M; Sá, L; Gonçalves, E; Pinto, M; Duarte, RObjectives: This study evaluated the effectiveness of COVID-19 vaccines in preventing symptomatic and severe disease.Study design: This was an observational test-negative case-control study.Methods: Study participants were adults with at least one symptom included in the World Health Or-ganization COVID-19 definition who sought health care in a public emergency department between 1 November 2021 and 2 March 202...
Engineering Hydrogels with Affinity-Bound Laminin as 3D Neural Stem Cell Cultur...
Barros, D; Conde-Sousa, E; Gonçalves, AM; Han, WM; García, AJ; Amaral, IF; Pêgo, APLaminin incorporation into biological or synthetic hydrogels has been explored to recapitulate the dynamic nature and biological complexity of neural stem cell (NSC) niches. However, the strategies currently explored for laminin immobilization within three-dimensional (3D) matrices do not address a critical aspect influencing cell-matrix interactions, which is the control over laminin conformation and orientati...
Combined tools for Surgical Case Packages contents and cost optimization: a pre...
Alves, AC; Gonçalves, AM; Fernandes, JM; Vaz, I; Teixeira, S; Sousa, I; Pereira, JJ; Dória-Nóbrega, SThis paper presents a solution proposal based on mathematical and statistical tools to optimize Surgical Case Packages of an Operating Room (OR) in a Portuguese public hospital that it is the most complex environment in a hospital. In this particular hospital, more than 27000 surgeries/year are performed, employing, sometimes, misadjusted composition of standard surgical packages and non-optimized grouping of s...
Renal Disease in Madeira Islands: Twenty-Seven Years' Experience of Native Kidn...
Vieira, P; Gonçalves, AM; Durães, JM; Rosa, N; Resende, L; Silva, G; Alves Teixeira; Rodrigues, F; Galvão, MJ; Brinca, A; Viana, H; Carvalho, FIntroduction: Renal biopsy plays an essential role either in the diagnosis or in the prognosis of patients with renal disease. In order to assess its epidemiology and evolution in Madeira Islands, we analysed twenty-seven years of native kidney biopsies. Methods: We performed a retrospective analysis of clinical records, including histological revision from 1986 to 2012, totalling 315 native kidney biopsies. Th...
Amilina: Hormona Pancreática de Glucorregulação
Gonçalves, AM; Esteves, MC; Caldeira, JA diabetes tipo I e os estadios avançados de diabetes tipo II são caracterizados por alterações do metabolismo glucídico resultantes da lesão da célula ß pancreática, com consequente perda da secreção de insulina. É elevado o número de doentes em que, apesar das adequadas medidas terapêuticas, o bom controle metabólico, tão necessário na prevenção das complicações tardias, é difícil de ser alcançado. As alteraç...