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Glucose metabolism reprogramming in bladder cancer: hexokinase 2 (HK2) as progn...
Afonso, Julieta; Gonçalves, Céline; Costa, Marta; Ferreira, Débora Carina Gonçalves Abreu; Santos, Lúcio; Longatto-Filho, Adhemar; Baltazar, FátimaProliferating cancer cells are able to reprogram their energy metabolism, favouring glycolysis even in the presence of oxygen and fully functioning mitochondria. Research is needed to validate the glycolysis-related proteins as prognostic/predictive biomarkers in urothelial bladder carcinoma (UBC), a malignancy tagged by high recurrence rates and poor response to chemotherapy. Here, we assessed GLUT1, HK2, PFKL...
Data: 2023
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Origem: RepositóriUM - Universidade do Minho