Introdução: O Fenómeno de Raynaud (FR) é uma isquemia transitória das extremidades e pode dividir-se em primário e secundário a várias patologias ou fármacos, como os betabloqueadores. A prevalência deste fenómeno pode variar entre 7-14,7%. A patofisiologia é pouco conhecida. A utilização de betabloqueadores com maior afinidade para os adrenorrecetores beta-1, como o bisoprolol, não será protetora do desenvolvi...
Composition and structure of oleogels significantly influence their digestive behaviour, impacting triacylglycerol breakdown and the bioavailability of incorporated compounds. Texture profile analysis showed that sterol-based oleogels (STOs) exhibited 20 times higher hardness than beeswax-based oleogels (BWOs), which showed stronger cohesion due to elasticity sustained by adhesive forces. Tribological assessmen...
The use of active methodologies in education brings countless potentialities to the teaching-learning process. In this context, this communication emerges from the intervention project “Origins of the sea: between tides and memories”, developed in the 1st Cycle of Basic Education, within the scope of the Supervised Educational Practice of the Master's Degree in Preschool Education and Teaching of the 1st Cycle ...
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Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype affecting mostly younger women with a poor 5-year overall survival. It is characterized by a high metastization rate, particularly to the brain, where the blood-brain barrier (BBB) hinders the pharmaceuticals delivery. New anticancer drugs able to inhibit cell migration are required to effectively prevent the development of metastasis. ...
The Time2Act@SDG Erasmus+ project aims to give higher education institutions the know-how and expertise they need to tackle the Sustainable Development Goals (SDGs) head on. The project offers three MOOC on the environment, the economy, and social issues. They provide a comprehensive approach to sustainability education that aligns with the principles of Education for Sustainable Development (ESD). The MOOC use...
Introduction: listeria monocytogenes is a significant foodborne pathogen capable of causing severe listeriosis, particularly in vulnerable people [1]. To prevent its spread, effective disinfection strategies are essential. Quaternary ammonium compounds, like benzalkonium chloride, and peracetic acid are commonly used biocides in food processing environments. However, L. monocytogenes can exhibit remarkable resi...
Listeria monocytogenes is a Gram-positive pathogenic bacterium that can cause listeriosis in humans [1,2]. A primary cause of human listeriosis is the consumption of food contaminated with L. monocytogenes. This rare yet severe foodborne illness results in high rates of hospitalization and mortality, particularly in vulnerable groups: the elderly, immunocompromised individuals, and pregnant women [3,4,5]. It ex...
Introduction: Listeria monocytogenes is a gram-positive pathogenic bacterium responsible for listeriosis in humans and other animals. Human listeriosis is primarily caused by the consumption of foods contaminated with L. monocytogenes. Although rare, this severe foodborne infection leads to high rates of hospitalization and mortality, particularly among vulnerable groups such as the elderly, immunocompromised i...
Introduction: Listeria monocytogenes is a gram-positive pathogenic bacterium that causes severe foodborne listeriosis in humans, transmitted through contaminated foods, with high hospitalization and mortality rates, particularly affecting vulnerable groups: the elderly, immunocompromised individuals, and pregnant women [1]. Quaternary ammonium compounds, such as benzalkonium chloride, are widely used as biocide...