Wilson disease (WD) is a genetic disorder of copper metabolism caused by mutations in the ATP7B gene resulting in toxic copper accumulation in several organs. WD can manifest as liver disease, a progressive neurological disorder, a psychiatric illness, or a combination of these. Other clinical manifestations can also occur. Diagnosis is challenging and typically requires a range of biochemical tests, imaging, g...
The Hepatitis C Virus (HCV) is a significant public health challenge in European countries. Historically, healthcare-related procedures were the primary source of HCV infection in Europe. However, with the implementation of blood safety programs, injection drug use has become the main transmission route. The infection's distribution and genotype prevalence vary widely across the continent. Even with the availab...
O Programa Oficina Social nasce no município de Cascais onde a Rede Social, enquanto estrutura de governança local, assume um papel centrado na responsabilidade partilhada na prossecução do desenvolvimento social do território e da coesão social. Nesse sentido, este Programa caracteriza‐se essencialmente por um trabalho em rede e em parceria com diversas instituições locais e a Escola Superior de Saúde do Alcoi...
Purpose - To analyze the extent to which recognition of impairments in goodwill is associated with periods of negative results before these losses (big bath practices). To determine whether indebtedness and the capital market restrict the recognition of such losses in big bath practices. Design/methodology/approach - Quantitative empirical study based on accounting and market data of companies listed on the Lis...
In this study a theoretical model of five dimensions is explained – Rest (1986) ethical decision making process; Jones (1991) moral intensity; need for cognition; personal attributes and financial information - in order to understand the conditions that lead policymakers to manipulate information and to understand the ethical issues in decision-making that lead or not, to a more useful accounting. The sample, b...
Esta investigação pretende determinar a importância dos componentes do outro rendimento integral para o resultado integral e a sua relevância para o valor de mercado das entidades. Este estudo recorreu à análise bi e multivariada e aos modelos do preço e do retorno. Encontrou-se evidência que o outro resultado integral é, em regra, negativo e representa uma percentagem significativa do resultado integral. Desta...
Purpose - To analyze recognition of impairment losses in tangible and intangible assets, and their relevance to investors in companies listed in the Lisbon and Madrid Stock Exchange (2007-2011).Methodology - Quantitative analysis of a panel data sample of 80 companies listed in the Lisbon and Madrid Stock Exchange (2007-2011) was carried out. Panel data linear and non-linear regression models were estimated.Fin...
Exposure to solar ultraviolet radiations is well known as an important factor on skin cancer development. In Portugal, outdoor workers are too long exposed to the sun, and consequently to the ultraviolet radiation effects. Sun protection behaviors are important to the prevention of skin cancer.
A Escola, através dos professores de Educação Física, é um espaço de excelência de promoção da atividade física. A percentagem da população jovem que tem excesso de peso e obesidade duplicou nas últimas décadas na Região Autónoma da Madeira. Em adição, a maioria dos alunos não se envolvem na prática de atividades desportivas dentro e fora do contexto escolar. Os objetivos do presente estudo foram: (1) Refletir ...