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Spontaneous Pneumomediastinum: A Rare Cause of Chest Pain

Barroso, Daniela; Rocha, Diana I.; Abelha Pereira, Filipa; Ribeiro, Rui; Pimenta Fernandes, João; Pais Monteiro, Ana; Silva, Isabel Fonseca

Spontaneous pneumomediastinum is a rare medical condition characterized by the presence of free air in the mediastinum, not preceded by trauma, surgery, or another medical procedure. It predominantly affects young adult males and usually has a benign course, and in most cases, it is not possible to identify the precipitating factor. There are some conditions that predispose to its occurrence, namely those that ...


Transitioning intravenous epoprostenol to oral selexipag in idiopathic pulmonar...

Alexandre, André; Furtado, Inês; Gonçalves, Fabienne; Gonçalves, Fabienne; Melo, Alzira; Alves, Joana; Santos, Mario; Reis, Abilio

Intravenous (i.v.) prostacyclin is the cornerstone treatment in high-risk pulmonary arterial hypertension (PAH) patients. Selexipag is an orally available prostacyclin receptor agonist. Limited data are available regarding the feasibility of transitioning from i.v. epoprostenol to selexipag. A 50-year-old woman with idiopathic PAH was diagnosed in a World Health Organization (WHO) Functional Class (FC) IV. She ...


Health-related quality of life in pulmonary hypertension and its clinical corre...

Reis, Abílio; Santos, Mário; Vicente, Margarida; Furtado, Inês; Cruz, Célia; Melo, Alzira; Carvalho, Luísa; Gonçalves, Fabienne; Almeida, Luís

Background: Health-related quality of life (HRQoL) impairment is common in pulmonary hypertension (PH), but its clinical predictors are not well established. This study aims to characterize the HRQoL of patients with pulmonary arterial hypertension (PAH) and other precapillary forms of PH (pcPH) and to explore its clinical correlates. Materials and Methods: A cross-sectional, observational study of patients wit...


Crowned Dens Syndrome

Maia Cruz, Célia; Vigário, Ana; Fonseca, Liliana; Gonçalves, Fabienne


Behçet disease and lymphoma. Casual association?

Ferreira, João Pedro; Gonçalves, Fabienne; Araújo Correia, João; Xavier, Luciana; Farrajota, Pedro

Behcet disease (BD) is characterized by a triple-symptom complex of recurrent oral aphthous ulcers, genital ulcers, and uveitis.Systemic involvement of multiple organs is observed in Behçet disease, based primarily in the development of vasculitis or vasculopathies lesions in the affected areas. These areas may demonstrate microscopic evidence of inflammatory tissue infiltration with both T cells and neutrophil...


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