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Detection of hepatitis E virus genotype 3 in an Algerian mouse (Mus spretus) in...

Santos-Silva, S; Moraes, DFDSD; López-López, P; Paupério, J; Queirós, J; Rivero-Juarez, A; Lux, L; Ulrich, RG; Gonçalves, HMR; Van der Poel, WHM

Virus monitoring in small mammals is central to the design of epidemiological control strategies for rodent-borne zoonotic viruses. Synanthropic small mammals are versatile and may be potential carriers of several microbial agents. In the present work, a total of 330 fecal samples of small mammals were collected at two sites in the North of Portugal and screened for zoonotic hepatitis E virus (HEV, species Pasl...


Hepatitis E virus in wild and domestic rabbits from Portugal: a combined molecu...

Santos-Silva, S; Santos, N; López-López, P; Nascimento, MSJ; Gonçalves, HMR; Van der Poel, WHM; Rivero-Juarez, A; Mesquita, JR

Hepatitis E virus (HEV), species Paslahepevirus balayani, poses a global public health threat, especially in developing countries, by causing acute enterically transmitted hepatitis. HEV infects various mammalian hosts and belongs to the genus Paslahepevirus in the family Hepeviridae. While swine are recognized as the main hosts of HEV, rabbits, which can also be affected by swine HEV-3 related strains, serve a...


Serological and Molecular Survey of Hepatitis E Virus in Small Ruminants from C...

Santos-Silva, S; Romalde, JL; Bento, JT; Cruz, AVS; López-López, P; Gonçalves, HMR; Van der Poel, WHM; Nascimento, MSJ; Rivero-Juarez, A; Mesquita, JR

Hepatitis E virus (HEV) is currently recognized as an emerging problem and a growing concern for public health in developed countries, with HEV infections mainly attributable to foodborne transmission of HEV-3. The zoonotic HEV genotype 3 infects a wide range of mammalian hosts, with swine considered as the primary host. This study investigates the occurrence of HEV among small ruminants in Portugal. The primar...


A Systematic Review and Meta-Analysis on Hepatitis E Virus Detection in Farmed ...

Santos-Silva, S; López-López, P; Gonçalves, HMR; Rivero-Juarez, A; Van der Poel, WHM; Nascimento, MSJ; Mesquita, JR

Swine are widely recognized as the main reservoir of zoonotic HEV; however, a growing body of data on the HEV prevalence in farmed ruminants of different species also points to a potential route for HEV transmission through ruminants and ruminant products and by-products. Definite information on the zoonotic potential of ruminants is still absent or unclear, compelling the necessity for increasing knowledge on ...


A Systematic Review of Hepatitis E Virus Detection in Camels

Santos-Silva, S; Hemnani, M; Lopez-Lopez, P; Gonçalves, HMR; Rivero-Juarez, A; van der Poel, WHM; Nascimento, MSJ; Mesquita, JR

Simple Summary: Acute hepatitis, which is a rising public health issue globally, is mostly caused by the hepatitis E virus (HEV). There is a potential risk of camel-borne zoonotic HEV infection in the desert regions of the Middle East and Africa, where camels frequently interact with human populations and camel-derived food products constitute a component of the food chain. To better understand the current stat...


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