5 documents found, page 1 of 1
Clinical trial for uniform multidrug therapy for leprosy patients in Brazil (U-...
Cruz, Rossilene Conceição da Silva; Bührer-Sékula, Samira; Penna, Gerson Oliveira; Moraes, Maria Elisabete Amaral de; Gonçalves, Heitor de SáBACKGROUND: The Clinical Trial for Uniform Multidrug Therapy for Leprosy Patients in Brazil (U-MDT/CT-BR), designed to evaluate the effectiveness of a six-months regimen, assessed the adverse effects caused by the drugs. OBJECTIVE: Describe adverse effects due to MDT in U-MDT/CT-BR, comparing the uniform regimen (U-MDT) to the current WHO regimen (R-MDT). Patients and methods: After operational classification, ...
Uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): results...
Penna, Gerson Oliveira; Bührer-Sékula, Samira; Kerr, Ligia Regina Franco Sansigolo; Rodrigues, Laura Cunha; Araújo, Marcelo Grossi deBackground Leprosy control is based on early diagnosis and multidrug therapy. For treatment purposes, leprosy patients can be classified as paucibacillary (PB) or multibacillary (MB), according to the number of skin lesions. Studies regarding a uniform treatment regimen (U-MDT) for all leprosy patients have been encouraged by the WHO, rendering disease classification unnecessary. Methodology and findings An ind...
Penfigoide gestacional: relato de caso e a importância do diagnóstico precoce
Botelho, Karine Paschoal; Barroso, Caroline Braga; Costa, Igor Santos; Gonçalves, Heitor de Sá; Pontes, Maria AraciO penfigoide gestacional é uma rara dermatose bolhosa autoimune específica da gravidez. Acredita-se que anticorpos ataquem antígenos epidérmicos específicos e provoquem a separação da junção dermoepidérmica da pele e a formação de bolhas. O quadro em geral se inicia com placas eritematosas pruriginosas periumbilicais com posterior disseminação pelo corpo e evolução para lesões bolhosas. Acomete principalmente p...
A clinical trial for uniform multidrug therapy for leprosy patients in Brazil :...
Penna, Gerson Oliveira; Pontes, Maria Araci de Andrade; Cruz, Rossilene Conceição da Silva; Gonçalves, Heitor de Sá; Penna, Maria Lúcia FernandesLeprosy will continue to be a public health problem for several decades. The World Health Organization (WHO) recommends that, for treatment purposes, leprosy cases be classified as either paucibacillary or multibacillary (MB). A uniform leprosy treatment regimen would simplify treatment and halve the treatment duration for MB patients. The clinical trial for uniform multidrug therapy (U-MDT) for leprosy patient...
Esquema único de tratamento da hanseníase : influências das formas clínicas nos...
Gonçalves, Heitor de SáLeprosy control is based on early treatment of the patient and interruption of transmission. On current days, a new challenge for this control presents itself: the applicability of one single treatment regimen for all clinical forms of the disease, denominated Uniform Multidrug Therapy (U-MDT), an effective and short regimen, capable of overcoming the following issues: mistakes in the classification of clinical...