A Tuberculose é uma doença infeciosa causada pelo Mycobacterium tuberculosis que, apesar do tratamento disponível, constitui uma causa de morbimortalidade global significativa. Pode atingir qualquer órgão, mas afeta principalmente o pulmão, sendo a via aérea, pela inalação de aerossóis ou microgotículas respiratórias contaminadas, a principal forma de infeção. O esforço global nas últimas décadas para um diagnó...
To assess the association between the number of allergen sensitizations and lung function variables in individuals with airway symptoms. Methods. Retrospective study with all individuals who performed lung function and skin-prick tests at CUF-Porto (01/2011-06/2016). Six allergen groups were considered. % predicted Pre-Bronchodilator test (BD) and % change after BD were analysed for spirometry and plethysmograp...
O número de sensibilizações a aeroalergénios é importante na classificação fenotípica de indivíduos com patologia das vias aéreas, estando um maior número associado a maior gravidade da patologia (Amaral R et al, Allergy 2019). No entanto, a sua associação com a função respiratória não está ainda estudada.
Lung function tests are critical for diagnosis and monitoring of asthma and other respiratory diseases. Monitoring of lung function, in the absence of a healthcare professional, is very challenging but may be obtained through Smart Devices if automated quality assessment systems guarantee the proper technique during the forced expiratory manoeuvre. This paper describes the evaluation of one such system that use...
Rhinomanometry is a simple and useful method for objective evaluation of nasal airway patency. However, there is a lack of published studies in pediatric patients. We aimed to evaluate nasal patency assessed by rhinomanometry and its variation after administration of an intranasal vasoconstrictor in children.
Introduction: Brugada syndrome (BrS) patients (pts) with spontaneous type 1 electrocardiographic (ECG) pattern (sT1ECGp) have a greater arrhythmic risk compared to those with fleicainide-induced type 1 ECG pattern (iT1ECGp). However, when the analysis is restricted to asymptomatic pts, the type 1 spontaneous pattern loses its independent prognostic value. Late potentials (LP) obtained by signal-averaged ECG (SA...
Introduction: Invasive hemodynamic evaluation is a fundamental diagnostic method in patients with pulmonary hypertension (PH). However, its prognostic value in this group of patients is not fully established. Purpose: To assess the prognostic impact of hemodynamic parameters of right catheterization in patients with PH. Methods: Prospective observational study of patients with PH undergoing right and left cathe...
Introduction: Pulmonary hypertension (PH) comprises a group of progressive diseases characterized by an increase in pulmonary vascular resistance, leading to right ventricular dysfunction. Risk stratification is essential for prognostic evaluation and therapeutic decision, making the determination of new biomarkers important. Purpose: To assess the prognostic value of new biomarkers in the prognostic evaluation...
Introduction: Implantable cardioverter defibrillator (ICD) and cardiac resynchronization (CRT-D) implantation in elderly patients is effective in preventing sudden death, although limited by the natural shorter life expectancy. The different device brands present very variable survival estimates and it has been discussed the availability of less expensive, less longevity generators for the elderly population. P...