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Cardiotoxicity in haematological diseases : are the tyrosine kinase inhibitors ...

Francisco, A. R. Gaspar Lopes; Alves, D.; Gonçalves, I. S.; Menezes, M. N.; Silva, G. Lima da; Guimarães, T.; David, C.; Braga, J.; Guerra, L.

Introduction: Chemotherapy-induced cardiotoxicity is a growing concern. The true cardiotoxic impact of new drugs such as tyrosine kinase inhibitors is unknown, especially the ones used for chronic myeloid leukaemia. We aim to evaluate nilotinib and imatinib induced cardiotoxicity. Methods: Single-center prospective study of consecutive patients with chronic myeloid leukaemia treated with tyrosine kinase inhibit...


Oxido-bis¬[chlorido(4,4'-di-tert-butyl-2,2'-bipyridine-2N,N')dioxido¬molybdenum...

Gomes, A. C.; Fernandes, J. A.; Gamelas ou Carla A. Gamelas, Carla; Gonçalves, I. S.; Almeida-Paz, F. A.

The title hydrate, [Mo2Cl2O5(C18H24N2)2]·0.2H2O, has been isolated as the oxidation product of [Mo(3-C3H5)Cl(CO)2(di-t-Bu-bipy)] (where di-t-Bu-bipy is 4,4'-di-tert-butyl-2,2'-bipyridine). A -oxide ligand bridges two similar MoCl(di-t-Bu-bipy)O2 units, having the terminal oxide ligands mutually cis, and the chloride and -oxide trans to each other. In the binuclear complex, the coordination geometries of the met...


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