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Polydimethylsiloxane surface modification of microfluidic devices for blood pla...
Gonçalves, Margarida; Gonçalves, Inês Maia; Borges, Joel; Faustino, Vera Luísa Carreira; Soares, Delfim; Vaz, Filipe; Minas, GraçaOver the last decade, researchers have developed a variety of new analytical and clinical diagnostic devices. These devices are predominantly based on microfluidic technologies, where biological samples can be processed and manipulated for the collection and detection of important biomolecules. Polydimethylsiloxane (PDMS) is the most commonly used material in the fabrication of these microfluidic devices. Howev...
Separation microfluidic device fabricated by micromilling techniques
Gonçalves, Inês Maia; Madureira, Miguel; Miranda, Inês; Schütte, Helmut; Moita, Ana; Minas, Graça; Gassmann, Stefan; Lima, Rui Alberto Madeira MacedoThe diagnosis of several diseases can be performed by analyzing the blood plasma of a patient. Despite extensive research work, there is still a need to improve current low-cost fabrication techniques and devices for the separation of plasma from blood cells. Microfluidic biomedical devices have great potential for that process. Hence, a microfluidic device made by micromilling and sealed with an oxygen plasma ...