22 documents found, page 1 of 3
Exercise preconditioning prevents left ventricular dysfunction and remodeling i...
Schmidt, Cristine; Bovolini, José A.; Gonçalves, Nádia; Vasques-Nóvoa, Francisco; Andrade, Maria do Amparo; Santos, Mário; Leite-Moreira, AdelinoBackground: Despite pulmonary arterial hypertension (PAH) directly affects the right ventricle (RV), important structural, functional, and molecular changes also occur in left ventricle (LV). The objective of our study was to analyze the hypothetical cardioprotective effects of exercise preconditioning on LV in rats with monocrotaline (MCT)-induced PAH. Methods: Forty male Wistar rats were randomly separated in...
Patient-specific outcome simulation after surgical correction of Pectus Excavat...
Couto, Mafalda Araújo Seara; Fonseca, João Luís Gomes; Moreira, António Herculano Jesus; Henriques-Coelho, Tiago; Fonseca, Jaime C.Although minimally invasive Nuss procedure is frequently performed to correct Pectus Excavatum, the successful aesthetical outcome is not always ensured. Using the computed tomography (CT) data of six patients, high-quality surfaces of the anterior chest wall were generated, alongside with a personalized corrective-bar. Through finite element method (FEM), replicating the surgical procedure, a simulation of the...
NEW CONCEPTS IN ADIPOSE TISSUE AND ABDOMINAL AORTIC PATHOLOGY
Dias-Neto, Marina; Nunes, Fábio; Almeida, Glória; Ramos, José Fernando; Teixeira, José Fernando; Sampaio, Sérgio; Leite-Moreira, AdelinoPerivascular adipose tissue has been increasingly recognized as an important producer of vasoactive factors and cytokines that may have a direct paracrine effect on the vasculature due to the inherent proximity. In this regard, perivascular adipose tissue-vessel interaction might be identified as a novel therapeutic target of vascular diseases. Conversely to other specific adipose depots, whose characteristics ...
A new methodology for assessment of pectus excavatum correction after bar remov...
Fonseca, João Luís Gomes; Vilaça, João Luis Araújo Martins; Henriques-Coelho, Tiago; Direito-Santos, Bruno; Pinho, António C.M.; Fonseca, Jaime C.Purpose: The objective is to present a new methodology to assess quantitatively the impact of bar removal on the anterior chest wall, among patients with pectus excavatum who have undergone the Nuss procedure, and present a preliminary study using this methodology. Methods: We propose to acquire, for each patient, the surface of the anterior chest wall using a three-dimensional laser scanner at subsequent time ...
Variations of the soft tissue thicknesses external to the ribs in pectus excava...
Rodrigues, Pedro L.; Direito-Santos, Bruno; Moreira, António H.J.; Fonseca, Jaime C.; Pinho, A.C.M.; F. Rodrigues, Nuno; Henriques-Coelho, TiagoBackground: Surgical repair of pectus excavatum (PE) has become more popular due to improvements in the minimally invasive Nuss procedure. The pre-surgical assessment of PE patients requires Computerized Tomography (CT), as the malformation characteristics vary from patient to patient. Objective: This work aims to characterize soft tissue thickness (STT) external to the ribs among PE patients. It also presents ...
Automatic prebent customized prosthesis for pectus excavatum minimally invasive...
Vilaça, João L.; Rodrigues, Pedro L.; Soares, Tony R.; Fonseca, Jaime; Pinho, ACM; Henriques-Coelho, Tiago; Correia-Pinto, JorgePectus excavatum is the most common deformity of the thorax. A minimally invasive surgical correction is commonly carried out to remodel the anterior chest wall by using an intrathoracic convex prosthesis in the substernal position. The process of prosthesis modeling and bending still remains an area of improvement. The authors developed a new system, i3DExcavatum, which can automatically model and bend the bar...
Automatic prebent customized prosthesis for pectus excavatum minimally invasive...
Vilaça, João L.; Rodrigues, Pedro L.; Soares, Tony R.; Fonseca, Jaime; Pinho, ACM; Henriques-Coelho, Tiago; Correia-Pinto, JorgePectus excavatum is the most common deformity of the thorax. A minimally invasive surgical correction is commonly carried out to remodel the anterior chest wall by using an intrathoracic convex prosthesis in the substernal position. The process of prosthesis modeling and bending still remains an area of improvement. The authors developed a new system, i3DExcavatum, which can automatically model and bend the bar...
Variations of the soft tissue thicknesses external to the ribs in Pectus Excava...
Rodrigues, Pedro L.; Direito-Santos, Bruno; Moreira, António H. J.; Fonseca, Jaime C.; Pinho, A.C.M.; F. Rodrigues, Nuno; Henriques-Coelho, TiagoBackground: Surgical repair of pectus excavatum (PE) has become more popular due to improvements in the minimally invasive Nuss procedure. The pre-surgical assessment of PE patients requires Computerized Tomography (CT), as the malformation characteristics vary from patient to patient. Objective: This work aims to characterize soft tissue thickness (STT) external to the ribs among PE patients. It also presents ...
Automatic prebent customized prosthesis for pectus excavatum minimally invasive...
Vilaça, João L.; Rodrigues, Pedro L.; Soares, Tony R.; Fonseca, Jaime C.; Pinho, António C.M.; Henriques-Coelho, Tiago; Correia-Pinto, JorgePectus excavatum is the most common deformity of the thorax. A minimally invasive surgical correction is commonly carried out to remodel the anterior chest wall by using an intrathoracic convex prosthesis in the substernal position. The process of prosthesis modeling and bending still remains an area of improvement. The authors developed a new system, i3DExcavatum, which can automatically model and bend the bar...
Finite element analysis of pectus carinatum surgical correction via a minimally...
Neves, Sara C.; Pinho, António C.M.; Fonseca, Jaime C.; F. Rodrigues, Nuno; Henriques-Coelho, Tiago; Correia-Pinto, Jorge; Vilaça, João L.Pectus carinatum (PC) is a chest deformity caused by a disproportionate growth of the costal cartilages compared to the bony thoracic skeleton, pulling the sternum towards, which leads to its protrusion. There has been a growing interest on using the ‘reversed Nuss’ technique as minimally invasive procedure for PC surgical correction. A corrective bar is introduced between the skin and the thoracic cage and pos...