78 documents found, page 1 of 8
Host−guest complexes of cyclopentadienyl iron dicarbonyl (CpFe(CO)2) CO-releasi...
Monteiro, Rodrigo P.; Calhau, Isabel B.; Gomes, Ana C.; Mendes, Ricardo F.; Paz, Filipe A. Almeida; D. Lopes, André; Silva, José Paulo daIron(II) cyclopentadienyl carbonyl complexes are promising as CO-releasing molecules (CORMs) for therapeutic applications. In common with other metallodrugs, the practical application of Fe-CORMs may require their conjugation with biocompatible carriers to improve their bioavailability and protect them from premature degradation. Here, we show that the CO-releasing properties of the complexes [CpFe(CO)2Cl] (1) ...
Host-guest complexes of cucurbit[8]uril and [(η5-C5H4R)Mo(CO)3CH3] (R = H, CO2C...
Gomes, Ana C.; Monteiro, Rodrigo P.; Calhau, Isabel B.; Lopes, André D.; Gonçalves, Isabel S.; Pillinger, MartynThe monosubstituted cyclopentadienyl half-sandwich molybdenum(II) tricarbonyl complex [(η5 -C5H4CO2CH3) Mo(CO)3CH3] (1) and its 1:1 inclusion compound with cucurbit[8]uril (1@CB8) have been prepared and characterised by elemental and thermogravimetric analyses, powder X-ray diffraction, diffuse reflectance UV–vis, solid-state 13C{1 H} MAS NMR, FT-IR, and Raman spectroscopies. The CO-releasing behaviours of 1, 1...
An organic-organometallic CO-releasing material comprising 4,4'-bipyridine and ...
Calhau, Isabel B.; Gomes, Ana C.; Mendes, Ricardo F.; Almeida Paz, Filipe A.; Gonçalves, Isabel S.; Pillinger, MartynOver the past two decades, following the discovery of the important biological roles of carbon monoxide (CO), metal carbonyl complexes have been intensively studied as CO-releasing molecules (CORMs) for therapeutic applications. To improve the properties of "bare" low molecular weight CORMs, attention has been drawn to conjugating CORMs with macromolecular and inorganic scaffolds to produce CO-releasing materia...
Inclusion complexes of cucurbit[n]urils (n = 7, 8) with η5‐cyclopentadienyl met...
Neves, Patrícia; Gomes, Ana C.; Monteiro, Rodrigo P.; Santos, Mirela J.; Valente, Anabela A.; Lopes, André D.; Gonçalves, Isabel S.; Pillinger, MartynThere are very few known examples of supramolecular compounds comprising molybdenum species hosted inside the portals/cavities of cucurbit[n]urils (CBn). In this work, CB7 and CB8 macrocycles have been studied as hosts for the carbonyl complex [CpMo(CO)3Me] (1) (Cp = η5-C5H5). Compounds were isolated in the solid state and characterized as genuine 1:1 inclusion complexes (1@CBn) by elemental and thermogravimetr...
Effect of 4,4′-dialkyl-2,2′-bipyridine ligands on the hydrolysis of dichlorodio...
Gomes, Diana M.; Gomes, Ana C.; Neves, Patrícia; Almeida Paz, Filipe A.; Valente, Anabela A.; Gonçalves, Isabel S.; Pillinger, MartynMolybdenum catalysts have been industrially recognized for decades for liquid phase epoxidation, which is an important chemical reaction process, since epoxides are used for many industrial applications. In this work, molybdenum oxide hybrid catalysts, prepared by a reflux hydrolysis methodology, performed effectively as heterogeneous catalysts or reaction-induced self-separating catalysts under mild reaction c...
Inclusion complexes of cucurbit[n]urils (n = 7, 8) with η5 -cyclopentadienyl me...
Neves, Patrícia; Gomes, Ana C.; Monteiro, Rodrigo P.; Santos, Mirela J.; Valente, Anabela A.; D. Lopes, André; Gonçalves, Isabel S.; Pillinger, MartynThere are very few known examples of supramolecular compounds comprising molybdenum species hosted inside the portals/cavities of cucurbit[n]urils (CBn). In this work, CB7 and CB8 macrocycles have been studied as hosts for the carbonyl complex [CpMo(CO)(3)Me] (1) (Cp = eta(5)-C5H5). Compounds were isolated in the solid state and characterized as genuine 1:1 inclusion complexes (1@CBn) by elemental and thermogra...
Host-guest complexes of cucurbit[8]uril and [(η5-C5H4R)Mo(CO)3CH3] (R = H, CO2C...
Gomes, Ana C.; Monteiro, Rodrigo P.; Calhau, Isabel B.; D. Lopes, André; Gonçalves, Isabel S.; Pillinger, MartynThe monosubstituted cyclopentadienyl half-sandwich molybdenum(II) tricarbonyl complex [(eta 5-C5H4CO2CH3) Mo(CO)3CH3] (1) and its 1:1 inclusion compound with cucurbit[8]uril (1@CB8) have been prepared and characterised by elemental and thermogravimetric analyses, powder X-ray diffraction, diffuse reflectance UV-vis, solid-state 13C{1H} MAS NMR, FT-IR, and Raman spectroscopies. The CO-releasing behaviours of 1, ...
Effect of β-cyclodextrin on the CO release kinetics and antimicrobial activity ...
Monteiro, Rodrigo P.; Calhau, Isabel B.; Gomes, Ana C.; Pereira, Carla; Vieira, Cátia; Faustino, M. Amparo F.; Almeida, Adelaide; Pillinger, MartynIn the present work the possibility of improving the solubility, bioavailability and bactericidal activity of the carbon monoxide releasing molecule (CORM) [Mo(CO)5Br]− (as its tetraethylammonium salt) (1) by solvent-free co-grinding with β-cyclodextrin (βCD) in a planetary ball mill was investigated. Data obtained by FT-IR spectroscopy, Raman spectroscopy, powder X-ray diffraction and thermogravimetric analysi...
Tricarbonyl-pyrazine-molybdenum(0) metal-organic frameworks for the storage and...
Silva, Andreia F.; Calhau, Isabel B.; Gomes, Ana C.; Valente, Anabela A.; Gonçalves, Isabel S.; Pillinger, MartynMetal-organic frameworks (MOFs) have high potential as nanoplatforms for the storage and delivery of therapeutic gasotransmitters or gas-releasing molecules. The aim of the present study was to open an investigation into the viability of tricarbonyl-pyrazine-molybdenum(0) MOFs as carbon monoxide-releasing materials (CORMAs). A previous investigation found that the reaction of Mo(CO)6 with excess pyrazine (pyz) ...
Reaction induced self-separating metal catalysts – Wonder systems in 21st centu...
Neves, Patrícia; Gomes, Diana M.; Gonçalves, Isabel S.; Pillinger, Martyn; Valente, Anabela A.The term Catalysis was first coined in the 19th century and has since been recognized as a fundamental field contributing to the greenness and sustainability of chemical processes. This inspiring field has many wonders. A discovery of the 21st century is reaction-controlled or reaction-induced self-separating (RISS) metal-based catalytic systems, essentially based on coordination compounds, which combine featur...