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Process standardization: the driving factor for bringing artificial intelligenc...

Silva, Joaquim P.; Gonçalves, Joaquim

Information Technology (IT) use is continuously broadening to new domains and applying to different applications. Today, Artificial Intelligence (AI) and management analytics are two of the most promising technologies that are being embedded into many applications. However, using AI and management analytics to solve specific problems and support decision-making requires custom developments and specialized perso...


A Pre-Diagnosis Model for Indoor Radon Potential Assessment

Meneses, Paulo; Lopes, Nuno; Leite, Patrícia; Texeira, Paulo; Gonçalves, Joaquim; Silva, joaquim P

Indoor radon is a well-known public health threat. WHO estimates radon causes between 3-14% of all lung cancers and has issued many recommendations to encourage countries to act against the exposure to radon and associated cancer risks. However, many people continue to be unaware about radon health risk. In previous works we developed a prediagnosis approach to evaluate the radon potential in indoor environment...


Feature Selection Optimization for Heart Rate Variability

Antunes, Ana Rita; Silva, Joaquim P.; Braga, Ana Cristina; Gonçalves, Joaquim

Feature selection optimization has gained attention since it helps extract good insights about a given subject. It is commonly used to reduce the dimensionality of the problem and to identify the best combination of features with aim of improving the prediction or classification model performance. Thereby, the present study intended to determine the best subset of features to classify the drowsiness state, into...


Dual-crosslinked injectable in situ forming Alginate/CaCl2/Pluronic F127/ α-Cyc...

Gonçalves, Joaquim; Melo, Bruna Daniela Lopes; Pouso, Manuel António do Rosário; Correia, Ilídio Joaquim Sobreira; de Melo-Diogo, Duarte

Injectable in situ forming hydrogels have been emerging due to their capacity to perform the direct delivery of therapeutics into the tumor site with minimal off-target leakage. Particularly, physical crosslinked injectable in situ forming hydrogels are appealing due to their straightforward preparation that exploits the native jointing capabilities of specific polymers/materials. However, the features of these...

Data: 2025   |   Origem: uBibliorum

Injectable and implantable hydrogels for localized delivery of drugs and nanoma...

Pouso, Manuel António do Rosário; Melo, Bruna Daniela Lopes; Gonçalves, Joaquim; Louro, Ricardo; Mendonça, António; Correia, Ilídio Joaquim Sobreira

Multiple chemotherapeutic strategies have been developed to tackle the complexity of cancer. Still, the outcome of chemotherapeutic regimens remains impaired by the drugs’ weak solubility, unspecific biodistribution and poor tumor accumulation after systemic administration. Such constraints triggered the development of nanomaterials to encapsulate and deliver anticancer drugs. In fact, the loading of drugs into...

Data: 2025   |   Origem: uBibliorum

Sleep quality of heavy vhicles’ professional drivers: an analysis based on self...

Faria, Brígida Mónica; Lopes, Tatiana; Oliveira, Alexandra; Pimenta, Rui; Gonçalves, Joaquim; Carvalho, Victor; Faria, Brigida Monica; Pimenta, Rui

Sleep is a crucial biological need for all individuals, being reparative on a physical and mental level. Driving heavy vehicles is a task that requires constant attention and vigilance, and sleep deprivation leads to behavioral and physiological changes that can develop sleep disorders which can put lives at risk The main objectives of this study are to describe and evaluate sleep quality, excessive daytime sle...


Development of dual-crosslinked Pluronic F127/Chitosan injectable hydrogels inc...

Pouso, Manuel António do Rosário; Melo, Bruna L.; Gonçalves, Joaquim; Mendonça, António; Correia, I.J.; Diogo, Duarte de Melo

Nanomaterials with responsiveness to near-infrared light can mediate the photoablation of cancer cells with an exceptional spatio-temporal resolution. However, the therapeutic outcome of this modality is limited by the nanostructures’ poor tumor uptake. To address this bottleneck, it is appealing to develop injectable in situ forming hydrogels due to their capacity to perform a tumor-confined delivery of the na...

Data: 2024   |   Origem: uBibliorum

Drowsiness transitions detection using a wearable device

Antunes, Ana Rita; Braga, A. C.; Gonçalves, Joaquim

Due to a reduction in reaction time and, consequently, the driver’s concentration, driving when fatigued has become an issue throughout time. Consequently, the likelihood of having an accident and it being fatal increases. In this work, we aim to identify an automatic method capable of detecting drowsiness transitions by considering the time, frequency, and nonlinear domains of heart rate variability. Therefore...


Feature selection optimization for heart rate variability

Antunes, Ana Rita Oliveira; Silva, Joaquim P.; Braga, A. C.; Gonçalves, Joaquim

Feature selection optimization has gained attention since it helps extract good insights about a given subject. It is commonly used to reduce the dimensionality of the problem and to identify the best combination of features with aim of improving the prediction or classification model performance. Thereby, the present study intended to determine the best subset of features to classify the drowsiness state, into...


Método de Ensino PBL versus Tradicional: Estudo de Caso

Patrícia, Leite; Gonçalves, Joaquim; Teixeira, Paulo; Silva, Joaquim P.

O método de ensino PBL foi uma aposta do grupo Iniciativa Nacional Competências Digitais e.2030 Portugal CoDigital 2030 selecionando alguns cursos de TeSP para a sua implementação. O IPCA implementou esta estratégia em dois cursos, de forma distinta e cujo impacto quis avaliar. Os resultados mostram que a implementação do PBL tem efeitos distintos dependendo das áreas científicas implementação. onde É é aplicad...

Data: 2022   |   Origem: CiencIPCA

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