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Self-Medication, Knowledge, Beliefs and Attitudes about Antibiotic Therapy in A...

Introduction: Antibiotics are widely used in pediatric respiratory conditions, despite most having a viral origin. Parental self-medication of children is also common. This study aimed to analyze the knowledge, beliefs, and attitudes of parents of children under 12 years old regarding antibiotic therapy and the practice of self-medication.Methodology: This was a multicenter, observational, descriptive, and cros...

Manuseio Anestésico da Lavagem Pulmonar em Homem com Proteinose Alveolar – Caso...

A proteinose alveolar é uma doença rara caracterizada pelo acúmulo alveolar de material lipoproteinaceo secundário ao processamento anormal de surfactante pelos macrófagos. O gold standard do tratamento consiste na lavagem pulmonar total. Descrevemos a complexidade do manuseio anestésico de um paciente com proteinose alveolar submetido a uma lavagem unipulmonar. Por ser uma patologia rara, a experiência no seu ...

Gestão anestésica de tirotoxicose em doença trofoblástica gestacional - caso cl...

A doença trofoblástica gestacional está associada a hipertiroidismo clínico e bioquímico. Nestas situações o estudo da função tiroideia é primordial, uma vez que a anestesia em doentes com hipertiroidismo correlaciona-se com uma maior taxa de complicações. Uma otimização pré-operatória com recurso a fármacos anti-tiroideus, beta-bloqueantes e corticoterapia é recomendada. O anestesiologista deve estar alerta pa...

Abordagem não convencional da via aérea pediátrica após trauma maxilo-facial

Vitamin D-related polymorphisms and vitamin D levels as risk biomarkers of COVI...

Vitamin D is a fundamental regulator of host defences by activating genes related to innate and adaptive immunity. Previous research shows a correlation between the levels of vitamin D in patients infected with SARS-CoV-2 and the degree of disease severity. This work investigates the impact of the genetic background related to vitamin D pathways on COVID-19 severity. For the first time, the Portuguese populatio...

Relatório de Estágio Curricular – Câmara Municipal (Porto)

O estágio curricular foi realizado no Gabinete de Comunicação e Promoção da Câmara Municipal do Porto. O presente relatório tem como objetivo apresentar os trabalhos e projetos desenvolvidos durante o período de estágio, devidamente fundamentados com os conhecimentos adquiridos na licenciatura em Comunicação Multimédia. O Gabinete de Comunicação e Promoção é insere-se na Direção Municipal da Presidência e, como...

ASA classification – What is the real impact of the introduction of the new cli...

Aim The American Society of Anesthesiologists scale is used worldwide for the assessment of the physical status of patients proposed for anaesthesia interventions. This study aims to assess the level of agreement of the last updated American Society of Anesthesiologists classification version, with the introduction of examples for each class, and search for variables that could promote inconsistency. Methods An...

Alpha-thalassemia due to novel deletions and complex rearrangements in the subt...

Introduction: Inherited deletions removing the α-globin genes and/or their upstream regulatory elements (MCSs) give rise to alpha-thalassemia, one of the most common genetic recessive disorders worldwide. The pathology is characterized by microcytic hypochromic anemia due to reduction of the α-globin chain synthesis, which are essential for hemoglobin tetramerization. Material and Methods: In order to clarify t...

Widening the spectrum of deletions and molecular mechanisms underlying alpha-th...

Inherited deletions of α-globin genes and/or their upstream regulatory elements (MCSs) give rise to α-thalassemia, an autosomal recessive microcytic hypochromic anemia. In this study, Multiplex Ligation-dependent Probe Amplification performed with commercial and synthetic engineered probes, Gap-PCR, and DNA sequencing were used to characterize lesions in the subtelomeric region of the short arm of chromosome 16...

Alpha-thalassemia due to novel deletions and complex rearrangements in the subt...

Introduction: Inherited deletions removing the α-globin genes and/or their upstream regulatory elements (MCSs) give rise to alpha-thalassemia, one of the most common genetic recessive disorders worldwide. The pathology is characterized by microcytic hypochromic anemia due to reduction of the α-globin chain synthesis, which are essential for hemoglobin tetramerization. Material and Methods: In order to clarify t...